HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 27368102, 33545068, 25042851
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006914 - autophagy
GO:0031625 - ubiquitin protein ligase binding
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 440
Hs

1 274
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024