Protein: SP4
Transcription factor Sp4 (SPR-1)

Gene: SP4
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q02446

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1036841

SP4
Transcription factor Sp4

2

17

High-throughput

0.783

High

1036844

VEZF1
Vascular endothelial zinc finger 1

2

19

High-throughput

0.783

High

1036852

VRK3
Serine/threonine-protein kinase VRK3

2

0

High-throughput

0.770

High

576218

PO2F1
POU domain, class 2, transcription factor 1

3

9

High-throughput

0.675

High

1036846

NRF1
Nuclear respiratory factor 1

3

2

High-throughput

0.675

High

926649

HIRA
Protein HIRA

2

8

High-throughput

0.628

High

586272

ZEP1
Zinc finger protein 40

1

20

High-throughput

0.621

High

1036858

CIB3
Calcium and integrin-binding family member 3

3

2

High-throughput

0.616

High

837037

ELK3
ETS domain-containing protein Elk-3

2

20

High-throughput

0.606

High

913245

TF2AA
Transcription initiation factor IIA subunit 1

2

2

High-throughput

0.606

High

1036843

NFYC
Nuclear transcription factor Y subunit gamma

2

10

High-throughput

0.606

High

1036851

POGZ
Pogo transposable element with ZNF domain

2

19

High-throughput

0.606

High

1036855

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.606

High

190057

FOXP2
Forkhead box protein P2

2

18

High-throughput

0.584

High

1036857

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1036859

PNKP
Bifunctional polynucleotide phosphatase/kinase

2

0

High-throughput

0.580

High

1036862

AP1M1
AP-1 complex subunit mu-1

2

0

High-throughput

0.580

High

1036863

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

2

0

High-throughput

0.580

High

614680

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

2

High-throughput

0.574

High

1029058

E2F1
Transcription factor E2F1

1

9

Small-scale

0.561

High

1036848

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

2

6

High-throughput

0.553

High

1036849

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

6

High-throughput

0.553

High

1036850

Q75MZ5
Forkhead box P2

2

1

High-throughput

0.544

High

1036853

BANP
Protein BANP

1

4

High-throughput

0.541

High

1036845

FHL2
Four and a half LIM domains protein 2

1

9

High-throughput

0.536

High

1017690

PR20A
Proline-rich protein 20A

2

2

High-throughput

0.533

High

694326

CO8A1
Collagen alpha-1(VIII) chain

1

3

High-throughput

0.523

High

1036842

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

1

High-throughput

0.523

High

1036854

LMO3
LIM domain only protein 3

1

12

High-throughput

0.523

High

1036856

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.501

High

277453

AVIL
Advillin

1

2

High-throughput

0.489

High

1036860

NKX31
Homeobox protein Nkx-3.1

1

19

Small-scale

0.481

High

1036864

HYPK
Huntingtin-interacting protein K

1

1

High-throughput

0.481

High

209986

CRX
Cone-rod homeobox protein

1

12

Small-scale

0.479

High

886773

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

1017608

PR20C
Proline-rich protein 20C

1

2

High-throughput

0.470

High

1017629

PR20D
Proline-rich protein 20D

1

2

High-throughput

0.470

High

1036861

Q9BTQ8
ATXN7L1 protein

1

4

High-throughput

0.470

High

1016329

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.460

High

75860

B4DE54
Protein BANP

1

4

High-throughput

0.457

High

1036865

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

1036866

AT7L1
Ataxin-7-like protein 1

1

7

High-throughput

0.439

High

3467

A0A0S2Z5G4
Protein BANP

1

4

High-throughput

0.417

High

1036867

PCDA4
Protocadherin alpha-4

1

0

High-throughput

0.279

Low

1036847

Q4G0S1
LOC730441 protein

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025