HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: LIMD1 (Q9UGP4)
LIM domain-containing protein 1
Gene: LIMD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 15870274
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 676
+	Mm
		1145368 SQSTM_MOUSE (1-440): 0: 731: 90.72		LIMD1_MOUSE (1-676): 7.61e-154: 462: 76.58
+	Hs
		1036815 SQSTM_HUMAN (1-440): 0: 760: 100.00		AJUBA_HUMAN (184-668): 3.37e-59: 210: 31.32
+	Hs
		1036977 SQSTM_HUMAN (1-440): 0: 760: 100.00		TES_HUMAN (349-654): 1.52e-56: 199: 20.32
+	Hs
		1036813 SQSTM_HUMAN (1-440): 0: 760: 100.00		PDLI5_HUMAN (182-669): 4.19e-29: 124: 13.09
+	Hs
		823388 SQSTM_HUMAN (1-440): 0: 760: 100.00		PAXI_HUMAN (537-674): 1.04e-25: 114: 25.33
+	Hs
		1036783 SQSTM_HUMAN (1-440): 0: 760: 100.00		LPP_HUMAN (160-669): 1.29e-13: 76.3: 13.69
+	Hs
		1036928 SQSTM_HUMAN (1-440): 0: 760: 100.00		PDLI7_HUMAN (153-524): 4.78e-13: 73.9: 11.41
+	Hs
		1036600 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRIP6_HUMAN (102-601): 1.09e-12: 72.8: 15.29
+	Hs
		1056032 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		ZYX_HUMAN (107-663): 6.52e-65: 226: 23.63
+	Hs
		1206026 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		PDLI5_HUMAN (182-669): 4.19e-29: 124: 13.09
+	Hs
		823434 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		PAXI_HUMAN (537-674): 1.04e-25: 114: 25.33
+	Hs
		238976 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		LPXN_HUMAN (536-674): 1.17e-25: 111: 25.83
+	Hs
		1056134 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		ZN160_HUMAN (223-499): 3.25e-45: 175: 6.86
+	Ce
		107647 Q9N3Z0_CAEEL (116-195): 3.78e-33: 126: 32.22		G5EFG1_CAEEL (533-669): 8.55e-24: 108: 20.86
+	Hs
		1076496 MIB2_HUMAN (106-264): 3.55e-23: 104: 26.09		TRIP6_HUMAN (102-601): 1.09e-12: 72.8: 15.29