HitPredict

Interactor 1: PRP4K (Q13523)
Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)
Gene: PRP4K

Interactor 2: LSM4 (Q9Y4Z0)
U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)
Gene: LSM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1007 Hs			1 139
+	Hs
		912286 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		SMD1_HUMAN (1-94): 4.78e-32: 111: 25.26
+	Hs
		911828 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82
+	Dm
		218364 DYRK2_DROME (612-1004): 1.73e-112: 365: 30.46		SMD3_DROME (2-112): 4.36e-30: 107: 30.63
+	Hs
		625313 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82