Interactor 1: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Interactor 2: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 22258451, 10608806, 28191891, 16027118
Identification Methods enzymatic study, unspecified method, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAT~FAT, FAT~FATC, FAT~PI3_PI4_kinase, FAT~UME, FATC~PI3_PI4_kinase, PI3_PI4_kinase~PI3_PI4_kinase
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000723 - telomere maintenance
GO:0003677 - DNA binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 39 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2644
Hs

1 2644
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+ At
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+ Xl
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+ Hs
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Last updated: 15 Jul 2024