Interactor 1: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR
Interactor 2: ATRIP (Q8WXE1)
ATR-interacting protein (ATM and Rad3-related-interacting protein)
Gene: ATRIP
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.768 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 14657349, 15210935, 11721054, 33961781, 17526493, 26854234, 15538388, 15743907, 23345434, 16027118, 20861269, 18344416, 18283122, 15451423, 17384638, 20847938, 15758953, 26212458, 17376433 and 7 others
more... |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, molecular sieving, ion exchange chromatography, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006139 - nucleobase-containing compound metabolic process GO:0006281 - DNA repair and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
