Protein: VTC1
Vacuolar transporter chaperone complex subunit 1 (Negative regulator of CDC42 protein 1) (Phosphate metabolism protein 4) (SPX-dependent polyphosphate polymerase VTC subunit 1) (Vacuolar membrane polyphosphate polymerase accessory subunit 1) (PolyP polymerase)

Gene: VTC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P40046

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0000421 - autophagosome membrane
GO:0003729 - mRNA binding
GO:0005774 - vacuolar membrane
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817481

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

4

15

Small-scale

0.890

High

817471

VTC2
Vacuolar transporter chaperone complex subunit 2

2

15

Small-scale

0.799

High

817474

VTC4
Vacuolar transporter chaperone complex subunit 4

2

15

Small-scale

0.789

High

740064

VPP1
V-type proton ATPase subunit a, vacuolar isoform

2

3

Small-scale

0.611

High

808346

VTC5
Vacuole transporter chaperone complex subunit 5

2

3

Small-scale

0.584

High

817485

NYV1
Vacuolar v-SNARE NYV1

2

3

Small-scale

0.584

High

817469

MEP2
Ammonium transporter MEP2

1

1

Small-scale

0.504

High

545023

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.504

High

817466

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.504

High

740338

SNQ2
Protein SNQ2

1

3

High-throughput

0.494

High

444528

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.479

High

547056

PPB
Repressible alkaline phosphatase

1

3

High-throughput

0.479

High

575727

BPT1
Bile pigment transporter 1

1

11

High-throughput

0.479

High

603481

VATA
V-type proton ATPase catalytic subunit A

1

6

High-throughput

0.479

High

618872

GAP1
General amino-acid permease GAP1

1

2

Small-scale

0.479

High

645828

VATE
V-type proton ATPase subunit E

1

3

High-throughput

0.479

High

673298

ADP1
Probable ATP-dependent permease

1

5

High-throughput

0.479

High

693189

PHO91
Low-affinity phosphate transporter PHO91

1

7

High-throughput

0.479

High

735725

VA0D
V-type proton ATPase subunit d

1

3

High-throughput

0.479

High

736186

YBT1
ATP-dependent bile acid permease

1

11

High-throughput

0.479

High

743687

VATD
V-type proton ATPase subunit D

1

3

High-throughput

0.479

High

746008

VATL2
V-type proton ATPase subunit c'

1

3

High-throughput

0.479

High

796492

PFF1
Vacuolar membrane protease

1

3

High-throughput

0.479

High

811613

YCFI
Metal resistance protein YCF1

1

11

High-throughput

0.479

High

811661

VATF
V-type proton ATPase subunit F

1

3

High-throughput

0.479

High

815863

KC13
Casein kinase I homolog 3

1

3

High-throughput

0.479

High

815967

VAC8
Vacuolar protein 8

1

3

High-throughput

0.479

High

817467

SYG1
Protein SYG1

1

7

High-throughput

0.479

High

817470

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

7

High-throughput

0.479

High

817472

RMD8
Sporulation protein RMD8

1

7

High-throughput

0.479

High

817475

VATG
V-type proton ATPase subunit G

1

3

High-throughput

0.479

High

817478

VOA1
V0 assembly protein 1

1

3

High-throughput

0.479

High

817479

VSB1
Vacuolar basic amino acid transporter VSB1

1

3

High-throughput

0.479

High

817482

RMD1
Sporulation protein RMD1

1

7

High-throughput

0.479

High

817486

YVC1
Calcium channel YVC1

1

3

High-throughput

0.479

High

817487

YPK9
Vacuolar cation-transporting ATPase YPK9

1

2

High-throughput

0.479

High

817489

VCX1
Vacuolar calcium ion transporter

1

7

High-throughput

0.479

High

577141

SEC63
Protein translocation protein SEC63

1

0

Small-scale

0.460

High

359241

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

812278

ATC3
Phospholipid-transporting ATPase DRS2

1

0

High-throughput

0.458

High

817468

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.458

High

817483

SKY1
Serine/threonine-protein kinase SKY1

1

1

High-throughput

0.457

High

817480

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.457

High

526798

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

817484

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.445

High

365060

KPYK1
Pyruvate kinase 1

1

2

High-throughput

0.437

High

558742

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

579469

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.437

High

707208

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

812335

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

816611

PXP1
2-hydroxyacyl-CoA lyase

1

2

High-throughput

0.437

High

760536

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

0

High-throughput

0.426

High

439350

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.407

High

742860

HSP79
Heat shock protein homolog SSE2

1

7

High-throughput

0.407

High

602478

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.261

Low

817473

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.261

Low

367246

ATP6
ATP synthase subunit a

1

0

Small-scale

0.249

Low

420940

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.249

Low

739970

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.249

Low

817477

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.249

Low

817488

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.249

Low

358229

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

432598

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

817476

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025