HitPredict

Interactor 1: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, proximity-dependent biotin identification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1124 Hs			1 2554
+	Hs
		720295 UFO_HUMAN (330-1106): 9.83e-161: 501: 23.47		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		650335 FGFR3_HUMAN (333-1119): 7.49e-160: 496: 23.03		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		1088201 MERTK_HUMAN (350-632): 2.97e-17: 89.7: 16.89		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		275871 EPHA2_HUMAN (383-1123): 2.29e-153: 484: 20.38		UBP12_HUMAN (1519-1957): 9.08e-94: 311: 21.51
+	Hs
		710158 EPHA2_HUMAN (383-1123): 2.29e-153: 484: 20.38		UBP46_HUMAN (1556-1957): 3.19e-92: 306: 20.56
+	Hs
		362338 ABL1_HUMAN (813-1098): 6.02e-56: 214: 38.51		UBP7_HUMAN (1469-2119): 6.29e-95: 336: 18.82