HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21179169
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 130
+	Hs
		391684 HDAC1_HUMAN (1-482): 0: 668: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470374 HDAC1_HUMAN (1-482): 0: 668: 100.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		1038643 HDAC1_HUMAN (1-482): 0: 668: 100.00		H2A1A_HUMAN (1-125): 8.62e-66: 197: 95.20
+	Hs
		1270389 HDAC2_HUMAN (1-478): 0: 666: 85.92		H2A1A_HUMAN (1-125): 8.62e-66: 197: 95.20
+	Hs
		1087070 HDAC2_HUMAN (1-478): 0: 666: 85.92		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		555567 HDAC2_HUMAN (1-478): 0: 666: 85.92		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		177360 HDAC3_HUMAN (9-434): 0: 574: 57.94		H2A1A_HUMAN (1-125): 8.62e-66: 197: 95.20
+	At
		286877 HDA6_ARATH (5-461): 0: 578: 58.04		H2A3_ARATH (1-128): 1.35e-60: 184: 72.87
+	Sp
		140568 PHD1_SCHPO (7-415): 0: 524: 52.91		H2A2_SCHPO (1-121): 7.25e-54: 167: 83.74
+	Sc
		392527 HDA1_YEAST (10-329): 4.19e-119: 366: 26.74		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Sc
		392177 HDA1_YEAST (10-329): 4.19e-119: 366: 26.74		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25
+	Hs
		391948 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470596 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46