HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: ZBTB2 (Q8N680)
Zinc finger and BTB domain-containing protein 2
Gene: ZBTB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	33301849, 26496610, 28514442, 33961781, 23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 514
+	Hs
		1235582 HDAC2_HUMAN (1-478): 0: 666: 85.92		ZBTB2_HUMAN (1-514): 0: 618: 100.00
+	Hs
		1038377 HDAC1_HUMAN (1-482): 0: 668: 100.00		ZN273_HUMAN (68-221): 1.77e-29: 123: 6.92
+	Hs
		1038838 HDAC1_HUMAN (1-482): 0: 668: 100.00		ZBTB1_HUMAN (1-97): 3.41e-16: 83.6: 46.47
+	Hs
		1193248 HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11		ZSCA2_HUMAN (298-513): 1.79e-99: 314: 18.43
+	Hs
		599074 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		ZNF10_HUMAN (252-466): 1.74e-13: 74.7: 27.31