Protein: SLU7
Pre-mRNA-splicing factor SLU7 (hSlu7)

Gene: SLU7
Organism: Homo sapiens
Interactions: 135
UniProt ID: O95391

Gene Ontology (top 5):
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000386 - second spliceosomal transesterification activity
GO:0000389 - mRNA 3'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335473

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.740

High

335507

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

7

0

Small-scale

0.718

High

335454

FHL3
Four and a half LIM domains protein 3

2

3

High-throughput

0.606

High

335414

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

2

High-throughput

0.586

High

335428

CRCM
Colorectal mutant cancer protein

2

0

High-throughput

0.580

High

335450

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

2

0

High-throughput

0.580

High

335465

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

0

High-throughput

0.580

High

335480

IKBD
NF-kappa-B inhibitor delta

2

0

High-throughput

0.580

High

335496

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

335508

DEFI6
Differentially expressed in FDCP 6 homolog

2

0

High-throughput

0.580

High

335530

NEMO
NF-kappa-B essential modulator

2

0

High-throughput

0.580

High

335504

NSD3
Histone-lysine N-methyltransferase NSD3

1

1

High-throughput

0.573

High

335412

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

215004

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.549

High

335452

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.549

High

335470

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.549

High

335479

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.549

High

335500

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.549

High

335513

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.549

High

130341

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.536

High

291889

WDHD1
WD repeat and HMG-box DNA-binding protein 1

1

1

High-throughput

0.536

High

335429

APC
Adenomatous polyposis coli protein

1

2

High-throughput

0.536

High

335438

NEST
Nestin

1

2

High-throughput

0.536

High

335445

MAP1A
Microtubule-associated protein 1A

1

1

High-throughput

0.536

High

335453

MTMR3
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

1

1

High-throughput

0.536

High

335455

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

335474

SPT6H
Transcription elongation factor SPT6

1

2

High-throughput

0.536

High

335489

LPP
Lipoma-preferred partner

1

3

High-throughput

0.536

High

335503

SETD2
Histone-lysine N-methyltransferase SETD2

1

1

High-throughput

0.536

High

335514

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

1

High-throughput

0.536

High

335529

SNX9
Sorting nexin-9

1

1

High-throughput

0.536

High

335462

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

335464

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.515

High

335423

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

144217

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

225236

HTSF1
17S U2 SnRNP complex component HTATSF1

1

0

High-throughput

0.513

High

272855

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

335420

SPTB1
Spectrin beta chain, erythrocytic

1

0

High-throughput

0.513

High

335478

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

0

High-throughput

0.513

High

335482

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.513

High

335490

KPBB
Phosphorylase b kinase regulatory subunit beta

1

0

High-throughput

0.513

High

335494

SCYL1
N-terminal kinase-like protein

1

0

High-throughput

0.513

High

335498

AKAP9
A-kinase anchor protein 9

1

0

High-throughput

0.513

High

335499

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

0

High-throughput

0.513

High

335510

COPRS
Coordinator of PRMT5 and differentiation stimulator

1

0

High-throughput

0.513

High

335512

RBM12
RNA-binding protein 12

1

0

High-throughput

0.513

High

335516

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

335517

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

0

High-throughput

0.513

High

335523

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

0

High-throughput

0.513

High

162417

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.508

High

335495

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.508

High

335416

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.493

High

335419

H14
Histone H1.4

1

0

High-throughput

0.493

High

335443

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.493

High

335483

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

335518

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

335463

AINX
Alpha-internexin

1

1

High-throughput

0.489

High

335497

SNX18
Sorting nexin-18

1

1

High-throughput

0.489

High

246364

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

335410

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.486

High

335451

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.486

High

335461

PCBP2
Poly(rC)-binding protein 2

1

0

High-throughput

0.486

High

335472

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.486

High

335481

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.486

High

335484

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

335444

GTF2I
General transcription factor II-I

1

0

Small-scale

0.480

High

142770

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

172365

XPO1
Exportin-1

1

1

High-throughput

0.479

High

335411

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

335415

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

335417

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

335437

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.479

High

335441

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

335447

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

335456

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

335457

DHX8
ATP-dependent RNA helicase DHX8

1

2

High-throughput

0.479

High

335459

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

335477

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

335487

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

335488

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

335501

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.479

High

335506

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

335509

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

335521

XPO7
Exportin-7

1

1

High-throughput

0.479

High

335525

SRRM2
Serine/arginine repetitive matrix protein 2

1

2

High-throughput

0.479

High

335467

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

335449

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

0

High-throughput

0.460

High

335524

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.460

High

190777

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

240373

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

335409

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

335418

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

335421

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

335422

LYL1
Protein lyl-1

1

0

High-throughput

0.458

High

335424

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

335425

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

335426

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

335430

DNMT1
DNA

1

0

Small-scale

0.458

High

335431

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

335432

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

335433

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

335434

PML
Protein PML

1

0

High-throughput

0.458

High

335435

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

335436

COIL
Coilin

1

0

High-throughput

0.458

High

335439

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

335440

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

335442

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

335448

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.458

High

335458

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

335460

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

335468

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.458

High

335471

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

335476

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

335485

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

335486

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

335491

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

335492

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

335493

DYL2
Dynein light chain 2, cytoplasmic

1

0

High-throughput

0.458

High

335502

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.458

High

335511

ANLN
Anillin

1

0

High-throughput

0.458

High

335515

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

335520

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

335526

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

335527

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

335528

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.458

High

335505

CRNL1
Crooked neck-like protein 1

1

2

High-throughput

0.445

High

335469

MYOME
Myomegalin

1

0

High-throughput

0.426

High

335446

GOGA2
Golgin subfamily A member 2

3

0

High-throughput

0.352

High

321885

FRYL
Protein furry homolog-like

1

0

High-throughput

0.279

Low

335466

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

335519

OPT
Opticin

1

0

High-throughput

0.279

Low

335427

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

335413

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

335522

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

335475

GPAM1
GPALPP motifs-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025