HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949739
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1893
+	Hs
		1038680 HDAC1_HUMAN (1-482): 0: 668: 100.00		CP250_HUMAN (118-1875): 1.86e-61: 236: 9.97
+	Hs
		1034610 HDAC2_HUMAN (1-478): 0: 666: 85.92		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		1038380 HDAC1_HUMAN (1-482): 0: 668: 100.00		GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		518865 HDAC1_HUMAN (1-482): 0: 668: 100.00		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		1038450 HDAC1_HUMAN (1-482): 0: 668: 100.00		MRCKA_HUMAN (51-491): 8.55e-24: 112: 14.26
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (1169-1882): 5.05e-23: 109: 10.61
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (1156-1882): 1.02e-19: 99.2: 11.08
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		148775 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		149134 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Hs
		551864 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (1-610): 8.41e-23: 109: 13.33
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (1278-1866): 1.41e-14: 82.2: 11.48
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48