HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000792 - heterochromatin GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 626
+	Hs
		1038580 HDAC1_HUMAN (1-482): 0: 668: 100.00		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Hs
		1270358 HDAC2_HUMAN (1-478): 0: 666: 85.92		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Sc
		693078 RPD3_YEAST (8-421): 0: 580: 61.48		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		903202 HDAC1_HUMAN (1-482): 0: 668: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		903404 HDAC2_HUMAN (1-478): 0: 666: 85.92		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		245600 HDAC1_HUMAN (1-482): 0: 668: 100.00		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Hs
		245623 HDAC2_HUMAN (1-478): 0: 666: 85.92		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Mm
		140272 HDAC1_MOUSE (1-482): 0: 672: 99.38		RBBP7_MOUSE (311-580): 1.59e-37: 146: 15.31
+	Mm
		936398 HDAC2_MOUSE (1-478): 0: 664: 85.71		RBBP7_MOUSE (311-580): 1.59e-37: 146: 15.31
+	Hs
		1270370 HDAC2_HUMAN (1-478): 0: 666: 85.92		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Mm
		140271 HDAC1_MOUSE (1-482): 0: 672: 99.38		RBBP4_MOUSE (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		997711 HDAC1_HUMAN (1-482): 0: 668: 100.00		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		997836 HDAC2_HUMAN (1-478): 0: 666: 85.92		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		177249 HDAC3_HUMAN (9-434): 0: 574: 57.94		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		177148 HDAC3_HUMAN (9-434): 0: 574: 57.94		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Ce
		184840 HDA1_CAEEL (3-455): 0: 605: 63.60		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73
+	Hs
		177278 HDAC3_HUMAN (9-434): 0: 574: 57.94		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		1260173 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		1028010 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		ERCC8_HUMAN (305-532): 1.35e-57: 200: 19.92
+	Hs
		245622 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67