HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	15388328
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 718
+	Mm
		140318 HDAC1_MOUSE (1-482): 0: 672: 99.38		MD1L1_MOUSE (1-716): 4.22e-60: 217: 80.31
+	Hs
		1270547 HDAC2_HUMAN (1-478): 0: 666: 85.92		MD1L1_HUMAN (1-718): 9.25e-62: 221: 100.00
+	Hs
		1038450 HDAC1_HUMAN (1-482): 0: 668: 100.00		MRCKA_HUMAN (164-708): 6.22e-43: 170: 17.69
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (1-542): 2.2e-19: 95.8: 7.17
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		148775 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		149134 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (421-698): 3.46e-12: 72.4: 11.51
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (393-713): 4.3e-12: 72: 11.53
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (421-698): 5.11e-11: 68.5: 11.51
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (421-698): 7.69e-11: 68.1: 11.51
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (421-698): 1.91e-10: 66.6: 11.87
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (393-713): 5.89e-12: 71.6: 11.53
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (393-713): 4.3e-12: 72: 11.53
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (3-368): 2.54e-10: 66.2: 9.04
+	Hs
		551864 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		1354183 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MRCKB_HUMAN (1-389): 1.46e-09: 63.8: 11.96
+	Hs
		1268107 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MY18A_HUMAN (44-521): 2.6e-09: 63: 15.87