HitPredict

Interactor 1: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	11278756, 18729074
Identification Methods	pull down, two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046332 - SMAD binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 467
+	Hs
		950169 SNW1_HUMAN (1-536): 0: 752: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		1035424 SNW1_HUMAN (1-536): 0: 752: 100.00		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58