HitPredict

Interactor 1: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.922

The method score is based on:

Property	Details
Experiments	28515276, 34079125, 20467437, 37071682, 12840015
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	PRO8NT~SKIP_SNW, PROCN~SKIP_SNW, RRM_4~SKIP_SNW
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck and 2 others more... GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	536
Hs

1	2335

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024