Protein: DCA11
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)

Gene: DCA11, DCAF11
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q8TEB1

Gene Ontology (top 5):
GO:0003016 - respiratory system process
GO:0005654 - nucleoplasm
GO:0006979 - response to oxidative stress
GO:0007613 - memory
GO:0010467 - gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1157828

DDB1
DNA damage-binding protein 1

15

20

Small-scale

0.984

High

1352267

DDA1
DET1- and DDB1-associated protein 1

5

3

Small-scale

0.927

High

610795

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.861

High

821472

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.861

High

876085

TCPE
T-complex protein 1 subunit epsilon

3

20

High-throughput

0.861

High

882059

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.861

High

899497

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.861

High

1007168

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.861

High

1352264

TCPH
T-complex protein 1 subunit eta

3

20

High-throughput

0.861

High

1114953

CUL4A
Cullin-4A

14

20

Small-scale

0.761

High

1115315

CUL4B
Cullin-4B

10

20

Small-scale

0.755

High

1272494

CSN6
COP9 signalosome complex subunit 6

9

1

Small-scale

0.752

High

1352251

CSN5
COP9 signalosome complex subunit 5

7

8

Small-scale

0.742

High

1352248

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.726

High

1352278

CSN7A
COP9 signalosome complex subunit 7a

5

2

High-throughput

0.718

High

958676

CSN2
COP9 signalosome complex subunit 2

5

5

High-throughput

0.712

High

1352283

CSN3
COP9 signalosome complex subunit 3

5

4

High-throughput

0.712

High

1352266

CSN4
COP9 signalosome complex subunit 4

4

1

High-throughput

0.694

High

1352281

APC4
Anaphase-promoting complex subunit 4

1

1

High-throughput

0.691

High

1352271

CSN7B
COP9 signalosome complex subunit 7b

3

2

High-throughput

0.667

High

1094382

CSN1
COP9 signalosome complex subunit 1

3

4

High-throughput

0.662

High

1126826

SLBP
Histone RNA hairpin-binding protein

2

1

Small-scale

0.653

High

1352262

CSN8
COP9 signalosome complex subunit 8

3

0

High-throughput

0.646

High

920137

PLK1
Serine/threonine-protein kinase PLK1

2

8

High-throughput

0.628

High

1156683

NF2L2
Nuclear factor erythroid 2-related factor 2

2

10

Small-scale

0.624

High

702817

5HT2C
5-hydroxytryptamine receptor 2C

1

1

High-throughput

0.618

High

957450

UBC12
NEDD8-conjugating enzyme Ubc12

1

6

High-throughput

0.618

High

992876

RACK1
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.618

High

1324973

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

16

High-throughput

0.618

High

1340759

COP1
E3 ubiquitin-protein ligase COP1

1

17

High-throughput

0.618

High

1352269

PDCL3
Phosducin-like protein 3

1

4

High-throughput

0.618

High

1352282

NOB1
RNA-binding protein NOB1

1

1

High-throughput

0.618

High

1352253

CUL5
Cullin-5

2

20

High-throughput

0.611

High

983900

RBX1
E3 ubiquitin-protein ligase RBX1

2

2

Small-scale

0.584

High

539372

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

2

3

High-throughput

0.574

High

1315583

MICU2
Calcium uptake protein 2, mitochondrial

2

2

High-throughput

0.574

High

808124

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.573

High

619254

TNNI1
Troponin I, slow skeletal muscle

2

1

High-throughput

0.553

High

877781

TNNI2
Troponin I, fast skeletal muscle

2

1

High-throughput

0.553

High

1295362

GPSM1
G-protein-signaling modulator 1

2

15

High-throughput

0.553

High

1254780

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

1154877

NEDD8
Ubiquitin-like protein NEDD8

1

2

High-throughput

0.536

High

1352274

PAR11
Protein mono-ADP-ribosyltransferase PARP11

1

6

High-throughput

0.536

High

1224875

TENS2
Tensin-2

2

5

High-throughput

0.526

High

1352252

GLMN
Glomulin

2

1

High-throughput

0.521

High

1352272

ELP3
Elongator complex protein 3

1

0

High-throughput

0.517

High

941817

ARL4C
ADP-ribosylation factor-like protein 4C

1

6

High-throughput

0.514

High

1227128

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.514

High

503629

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

1352246

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.513

High

1352270

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.513

High

1352279

FXL17
F-box/LRR-repeat protein 17

1

0

High-throughput

0.513

High

986858

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

4

Small-scale

0.512

High

384494

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.501

High

951773

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.501

High

1352268

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.494

High

1322332

ZN444
Zinc finger protein 444

1

1

High-throughput

0.489

High

1352265

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.489

High

1352273

MAGE1
Melanoma-associated antigen E1

1

5

High-throughput

0.489

High

1352276

TBCC1
TBCC domain-containing protein 1

1

1

High-throughput

0.489

High

1352254

TRI63
E3 ubiquitin-protein ligase TRIM63

1

13

High-throughput

0.481

High

124626

EYA2
Protein phosphatase EYA2

1

8

High-throughput

0.479

High

124813

AIP
AH receptor-interacting protein

1

7

High-throughput

0.479

High

128025

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

5

High-throughput

0.479

High

182166

PFD6
Prefoldin subunit 6

1

6

High-throughput

0.479

High

242382

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

346666

TTC4
Tetratricopeptide repeat protein 4

1

15

High-throughput

0.479

High

637651

FLNA
Filamin-A

1

10

High-throughput

0.479

High

667942

CDK2
Cyclin-dependent kinase 2

1

4

Small-scale

0.479

High

713173

NOS1
Nitric oxide synthase 1

1

1

High-throughput

0.479

High

831110

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

885595

PRI2
DNA primase large subunit

1

1

High-throughput

0.479

High

1093277

FLII
Protein flightless-1 homolog

1

2

High-throughput

0.479

High

1103284

CTBP1
C-terminal-binding protein 1

1

7

Small-scale

0.479

High

1113804

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1121474

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

1147216

ELOB
Elongin-B

1

1

High-throughput

0.479

High

1352259

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

3

Small-scale

0.479

High

1352261

NUP88
Nuclear pore complex protein Nup88

1

1

High-throughput

0.479

High

1352275

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

Small-scale

0.479

High

1352280

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1352284

RUVB2
RuvB-like 2

1

5

High-throughput

0.479

High

1352285

NUDC
Nuclear migration protein nudC

1

14

High-throughput

0.479

High

1352286

DRG1
Developmentally-regulated GTP-binding protein 1

1

5

High-throughput

0.479

High

1352289

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

551174

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

1092706

AF1Q
Protein AF1q

1

0

High-throughput

0.458

High

1119515

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

1352256

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.458

High

191721

MAGB2
Melanoma-associated antigen B2

1

5

High-throughput

0.437

High

248744

PEPL
Periplakin

1

15

High-throughput

0.437

High

451035

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.437

High

568455

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

587746

DESP
Desmoplakin

1

15

High-throughput

0.437

High

720783

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.437

High

895939

F10A1
Hsc70-interacting protein

1

7

High-throughput

0.437

High

906123

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.437

High

963337

PFD3
Prefoldin subunit 3

1

6

High-throughput

0.437

High

1026146

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.437

High

1241557

CEP85
Centrosomal protein of 85 kDa

1

18

High-throughput

0.437

High

1257736

VP13C
Intermembrane lipid transfer protein VPS13C

1

1

High-throughput

0.437

High

1277063

CC186
Coiled-coil domain-containing protein 186

1

6

High-throughput

0.437

High

1349297

TBC15
TBC1 domain family member 15

1

2

High-throughput

0.437

High

1352244

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

4

High-throughput

0.437

High

1352249

LPIN2
Phosphatidate phosphatase LPIN2

1

3

High-throughput

0.437

High

1352255

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.437

High

1352260

PFD5
Prefoldin subunit 5

1

7

High-throughput

0.437

High

1352290

GRIP1
Glutamate receptor-interacting protein 1

1

4

High-throughput

0.437

High

143747

WN10B
Protein Wnt-10b

1

0

High-throughput

0.426

High

1352247

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.426

High

1352277

CEP72
Centrosomal protein of 72 kDa

1

6

High-throughput

0.407

High

1352292

SRPRB
Signal recognition particle receptor subunit beta

1

6

High-throughput

0.407

High

183172

GNPAT
Dihydroxyacetone phosphate acyltransferase

2

0

High-throughput

0.328

High

1158069

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

0

High-throughput

0.328

High

1326197

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.318

High

353462

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

1145632

RCN1
Reticulocalbin-1

2

0

High-throughput

0.316

High

416635

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

1234464

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

1316038

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1352287

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

1352288

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.279

Low

176692

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.249

Low

348626

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.249

Low

922597

AP2S1
AP-2 complex subunit sigma

1

0

High-throughput

0.249

Low

1017796

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.249

Low

1120055

COTL1
Coactosin-like protein

1

0

High-throughput

0.249

Low

1217342

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.249

Low

1288483

LBN
Limbin

1

0

High-throughput

0.249

Low

1352245

OSCP1
Protein OSCP1

1

0

High-throughput

0.249

Low

1352250

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1352258

CDRTF
CMT1A duplicated region transcript 15 protein

1

0

High-throughput

0.249

Low

1352263

METH
Methionine synthase

1

0

High-throughput

0.249

Low

1352291

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.249

Low

880808

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.232

Low

1313968

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1352257

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025