HitPredict

Interactor 1: CREB5 (Q02930)
Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (cAMP-response element-binding protein A) (CRE-BPa)
Gene: CREB5

Interactor 2: KRA42 (Q9BYR5)
Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2)
Gene: KRTAP4-2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 136
+	Hs
		1039798 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR412_HUMAN (2-136): 5.19e-26: 98.6: 64.38
+	Hs
		1039783 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA13_HUMAN (3-135): 4.46e-22: 87.4: 34.57
+	Hs
		950049 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR105_HUMAN (26-135): 1.39e-16: 75.4: 36.80
+	Hs
		949854 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR103_HUMAN (35-136): 1.09e-16: 74.7: 36.36
+	Hs
		1039805 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA93_HUMAN (29-134): 6.36e-17: 73.9: 42.73
+	Hs
		950232 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR107_HUMAN (16-136): 3.48e-14: 69.7: 29.63
+	Hs
		1039809 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA45_HUMAN (2-136): 1.65e-14: 68.1: 41.21
+	Hs
		950454 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR108_HUMAN (14-136): 9.76e-14: 67.4: 27.48
+	Hs
		950746 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR109_HUMAN (4-116): 3.01e-13: 66.6: 30.53
+	Hs
		1039806 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA92_HUMAN (33-134): 1.36e-13: 65.8: 43.20
+	Hs
		1039807 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR411_HUMAN (52-136): 3.7e-13: 65: 47.06
+	Hs
		948710 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR10A_HUMAN (4-126): 2.34e-12: 63.5: 27.64
+	Hs
		1039804 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA94_HUMAN (34-136): 8.41e-13: 63.1: 42.72
+	Hs
		950924 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR10B_HUMAN (2-116): 1.77e-11: 61.6: 32.52
+	Hs
		1039808 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA41_HUMAN (2-70): 1.14e-11: 60: 56.52
+	Hs
		1039803 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA98_HUMAN (43-124): 2.54e-11: 59.3: 45.35
+	Hs
		949687 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR101_HUMAN (51-135): 9.59e-11: 59.3: 35.48
+	Hs
		505314 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA23_HUMAN (19-135): 7.75e-11: 57.3: 31.20
+	Hs
		949532 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KR123_HUMAN (51-136): 9.26e-11: 56.6: 33.33
+	Hs
		1039732 CREB5_HUMAN (1-508): 1.01e-96: 303: 100.00		KRA11_HUMAN (3-124): 1.34e-09: 55: 24.81