HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 238
+	Hs
		1040368 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		SRS12_HUMAN (1-218): 8.5e-28: 108: 32.60
+	Mm
		1161322 TRA2A_MOUSE (1-253): 1.8e-43: 151: 96.09		SRSF7_MOUSE (8-238): 3.54e-29: 112: 97.40
+	Dm
		580162 TRA2_DROME (97-281): 1.36e-44: 153: 43.78		RBP1_DROME (1-80): 1.02e-29: 109: 67.50
+	Hs
		432695 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		1031314 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		992758 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516502 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		516425 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		853881 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		474022 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		432527 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		516466 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Dm
		580166 TRA2_DROME (97-281): 1.36e-44: 153: 43.78		Q9V3W7_DROME (10-81): 1.07e-18: 83.8: 43.84
+	Hs
		516478 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516339 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		516495 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		474021 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		516471 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		TIAR_HUMAN (5-97): 6.64e-16: 77.8: 25.51
+	Hs
		516674 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33