HitPredict

Interactor 1: SNX1 (Q13596)
Sorting nexin-1
Gene: SNX1

Interactor 2: SNX32 (Q86XE0)
Sorting nexin-32 (Sorting nexin-6B)
Gene: SNX32

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.956

Property	Details
Experiments	21516116, 28514442, 33961781, 25416956, 32296183, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PX~PX, PX~Vps5, Vps5~Vps5
Common GO terms	GO:0005768 - endosome GO:0005829 - cytosol GO:0035091 - phosphatidylinositol binding GO:0042147 - retrograde transport, endosome to Golgi
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 403
+	Hs
		1040543 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		SNX5_HUMAN (10-400): 2.41e-108: 326: 62.40
+	Hs
		1040533 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		SNX6_HUMAN (14-402): 3.69e-106: 320: 69.67
+	Hs
		240386 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		SNX2_HUMAN (15-401): 1.09e-95: 297: 22.74
+	Hs
		240410 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		SNX32_HUMAN (1-403): 5.67e-117: 348: 100.00
+	Hs
		1040456 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		SNX1_HUMAN (26-401): 5.84e-89: 280: 22.42
+	Hs
		240464 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		SNX5_HUMAN (10-400): 2.41e-108: 326: 62.40
+	Hs
		240456 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		SNX6_HUMAN (14-402): 3.69e-106: 320: 69.67
+	Hs
		240317 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		SNX2_HUMAN (15-401): 1.09e-95: 297: 22.74
+	Dm
		1370164 Q9VQQ6_DROME (92-521): 7.8e-110: 336: 41.82		Q9VLQ9_DROME (18-400): 7.72e-105: 318: 55.09
+	Dm
		112640 X2J8I7_DROME (92-521): 1.38e-107: 330: 41.59		M9NDI3_DROME (18-400): 4.17e-102: 312: 54.50
+	Hs
		1040542 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		SNX8_HUMAN (33-399): 3.46e-53: 185: 16.63
+	Ce
		90270 Q9GYJ9_CAEEL (61-521): 5.85e-98: 306: 32.98		D9PTP5_CAEEL (15-401): 3.37e-95: 294: 49.49
+	Hs
		1261042 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		SNX33_HUMAN (2-400): 1.06e-86: 276: 13.53
+	Hs
		1300858 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		SNX9_HUMAN (2-399): 1.07e-83: 268: 15.24
+	Hs
		240322 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		SNX4_HUMAN (26-397): 6.98e-52: 181: 14.76
+	Hs
		1300849 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		SNX18_HUMAN (7-360): 4.18e-71: 236: 12.70
+	Ce
		1325795 Q9GYJ9_CAEEL (61-521): 5.85e-98: 306: 32.98		Q9GYJ9_CAEEL (36-400): 3.82e-69: 227: 18.18
+	Hs
		1300859 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		SNX8_HUMAN (33-399): 3.46e-53: 185: 16.63
+	Ce
		90278 Q9GYJ9_CAEEL (61-521): 5.85e-98: 306: 32.98		D9PTP8_CAEEL (271-401): 1.41e-36: 131: 51.91