Protein: GSTM3
Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3) (hGSTM3-3)

Gene: GSTM3
Organism: Homo sapiens
Interactions: 120
UniProt ID: P21266

Gene Ontology (top 5):
GO:0004364 - glutathione transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006749 - glutathione metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636815

GSTM3
Glutathione S-transferase Mu 3

7

14

High-throughput

0.966

High

636830

GSTM5
Glutathione S-transferase Mu 5

7

14

High-throughput

0.964

High

636842

GSTM4
Glutathione S-transferase Mu 4

7

15

High-throughput

0.962

High

636818

GSTM2
Glutathione S-transferase Mu 2

3

15

High-throughput

0.861

High

482709

GSTM1
Glutathione S-transferase Mu 1

1

15

High-throughput

0.698

High

636852

PLSI
Plastin-1

3

3

High-throughput

0.667

High

636871

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

3

1

High-throughput

0.667

High

636882

ASPP1
Apoptosis-stimulating of p53 protein 1

3

2

High-throughput

0.667

High

636904

TPX2
Targeting protein for Xklp2

3

1

High-throughput

0.667

High

636850

SLBP
Histone RNA hairpin-binding protein

3

0

High-throughput

0.638

High

636880

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

3

0

High-throughput

0.638

High

395486

ESR1
Estrogen receptor

3

2

Small-scale

0.633

High

636845

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

2

High-throughput

0.618

High

636888

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

2

0

High-throughput

0.585

High

636895

LANC2
LanC-like protein 2

2

0

High-throughput

0.585

High

636825

SPB5
Serpin B5

1

0

Small-scale

0.549

High

167818

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

7

High-throughput

0.536

High

343556

OXSR1
Serine/threonine-protein kinase OSR1

1

1

High-throughput

0.536

High

529068

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

636821

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

636824

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

6

High-throughput

0.536

High

636829

MK08
Mitogen-activated protein kinase 8

1

8

High-throughput

0.536

High

636837

FOXK1
Forkhead box protein K1

1

4

High-throughput

0.536

High

636838

VIGLN
Vigilin

1

1

High-throughput

0.536

High

636840

FOXK2
Forkhead box protein K2

1

4

High-throughput

0.536

High

636853

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

1

High-throughput

0.536

High

636868

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

1

High-throughput

0.536

High

636870

CTF18
Chromosome transmission fidelity protein 18 homolog

1

3

High-throughput

0.536

High

636873

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

2

High-throughput

0.536

High

636886

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.536

High

636894

WNK1
Serine/threonine-protein kinase WNK1

1

1

High-throughput

0.536

High

636898

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

3

High-throughput

0.536

High

636909

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.536

High

359791

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

636848

RIN1
Ras and Rab interactor 1

1

0

High-throughput

0.513

High

636855

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.513

High

636856

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.513

High

636864

BRAT1
Integrator complex assembly factor BRAT1

1

0

High-throughput

0.513

High

636867

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.513

High

636876

SYMPK
Symplekin

1

0

High-throughput

0.513

High

636881

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

636890

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

636905

TBD2B
TBC1 domain family member 2B

1

0

High-throughput

0.513

High

636883

SH3G2
Endophilin-A1

1

4

High-throughput

0.508

High

185424

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

636835

1433E
14-3-3 protein epsilon

1

2

Small-scale

0.501

High

636908

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

636819

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.493

High

137958

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.479

High

319391

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

320627

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

347525

BAG3
BAG family molecular chaperone regulator 3

1

4

High-throughput

0.479

High

587904

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

624217

TFE3
Transcription factor E3

1

1

High-throughput

0.479

High

636823

MSX2
Homeobox protein MSX-2

1

1

High-throughput

0.479

High

636826

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

636827

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

636828

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

636832

FOXA1
Hepatocyte nuclear factor 3-alpha

1

4

High-throughput

0.479

High

636833

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

636834

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

636846

PAK2
Serine/threonine-protein kinase PAK 2

1

3

High-throughput

0.479

High

636847

CUL3
Cullin-3

1

3

High-throughput

0.479

High

636849

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

636851

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

636854

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

636860

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

636865

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

636866

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

Small-scale

0.479

High

636872

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

636875

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

636877

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

636892

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

7

High-throughput

0.479

High

636893

ATG5
Autophagy protein 5

1

1

High-throughput

0.479

High

636900

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.479

High

636901

DJB11
DnaJ homolog subfamily B member 11

1

1

High-throughput

0.479

High

636902

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

636903

BAG5
BAG family molecular chaperone regulator 5

1

4

High-throughput

0.479

High

636907

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.479

High

636844

ZP4
Zona pellucida sperm-binding protein 4

1

1

Small-scale

0.470

High

370151

CYTN
Cystatin-SN

1

0

Small-scale

0.458

High

486953

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

520742

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.458

High

636817

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

636841

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

636862

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

636869

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

636884

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

636889

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

636897

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

636899

KLH42
Kelch-like protein 42

1

0

High-throughput

0.458

High

563187

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

636820

1433S
14-3-3 protein sigma

1

4

High-throughput

0.445

High

636836

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.445

High

636857

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

636859

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

105322

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

352957

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

636816

ZP3
Zona pellucida sperm-binding protein 3

1

1

Small-scale

0.437

High

636831

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

636879

KCD12
BTB/POZ domain-containing protein KCTD12

1

5

Small-scale

0.437

High

636843

RBL2
Retinoblastoma-like protein 2

1

0

Small-scale

0.426

High

636861

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

636874

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

466867

ACM4
Muscarinic acetylcholine receptor M4

1

1

High-throughput

0.407

High

636839

ECT2L
Epithelial cell-transforming sequence 2 oncogene-like

3

0

High-throughput

0.347

High

636858

CLVS2
Clavesin-2

2

0

High-throughput

0.316

High

636863

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

636878

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

636885

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.279

Low

636887

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

636896

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

217823

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

377172

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

590798

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.249

Low

636822

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

636906

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

261084

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

636891

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025