HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ARMC5 (Q96C12)
Armadillo repeat-containing protein 5
Gene: ARMC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	33961781, 35687106, 28514442, 33130828, 35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 935
+	Hs
		853273 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA1_HUMAN (90-448): 1.62e-54: 200: 20.91
+	Hs
		168634 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA6_HUMAN (61-430): 1.64e-42: 165: 16.58
+	Hs
		717062 CUL3_HUMAN (1-768): 0: 951: 100.00		CTNB1_HUMAN (38-519): 2.57e-35: 146: 16.36
+	Hs
		238673 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA7_HUMAN (64-326): 1.99e-26: 116: 17.16
+	Hs
		1042859 CUL3_HUMAN (1-768): 0: 951: 100.00		CTND2_HUMAN (51-400): 5.39e-14: 78.7: 15.60
+	Hs
		853274 CUL4B_HUMAN (5-768): 0: 779: 36.77		IMA1_HUMAN (90-448): 1.62e-54: 200: 20.91
+	At
		80978 CUL3A_ARATH (9-768): 0: 842: 51.45		ABAP1_ARATH (42-394): 4.78e-27: 120: 17.51
+	At
		80974 CUL3B_ARATH (9-768): 0: 826: 50.92		ABAP1_ARATH (42-394): 4.78e-27: 120: 17.51
+	Mm
		970126 CUL4A_MOUSE (5-768): 0: 796: 37.68		CTNB1_MOUSE (38-519): 6.94e-35: 145: 16.36
+	Hs
		717063 CUL4A_HUMAN (10-768): 0: 791: 38.32		CTNB1_HUMAN (38-519): 2.57e-35: 146: 16.36
+	Hs
		853272 CUL1_HUMAN (18-768): 0: 707: 30.57		IMA1_HUMAN (90-448): 1.62e-54: 200: 20.91
+	Hs
		717061 CUL1_HUMAN (18-768): 0: 707: 30.57		CTNB1_HUMAN (38-519): 2.57e-35: 146: 16.36