HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: ROAA (Q99729)
Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1)
Gene: HNRNPAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 332
+	Hs
		453345 CUL4B_HUMAN (10-759): 0: 927: 82.31		ROA1_HUMAN (58-235): 7.34e-71: 226: 38.38
+	Hs
		1042970 CUL4A_HUMAN (1-759): 0: 963: 100.00		HNRPD_HUMAN (32-332): 1.26e-55: 186: 55.63
+	Hs
		1043538 CUL4B_HUMAN (10-759): 0: 927: 82.31		ROAA_HUMAN (1-332): 2.58e-68: 218: 100.00
+	Hs
		162040 CUL4A_HUMAN (1-759): 0: 963: 100.00		HNRDL_HUMAN (12-332): 3.27e-51: 176: 49.85
+	Hs
		1043347 CUL4B_HUMAN (10-759): 0: 927: 82.31		HNRPD_HUMAN (32-332): 1.26e-55: 186: 55.63
+	Hs
		852051 CUL4B_HUMAN (10-759): 0: 927: 82.31		ROA3_HUMAN (36-237): 3.44e-53: 180: 36.36
+	Hs
		609852 CUL4A_HUMAN (1-759): 0: 963: 100.00		ROA2_HUMAN (63-246): 1.97e-38: 141: 38.22
+	Hs
		162041 CUL4B_HUMAN (10-759): 0: 927: 82.31		HNRDL_HUMAN (12-332): 3.27e-51: 176: 49.85
+	Hs
		609853 CUL4B_HUMAN (10-759): 0: 927: 82.31		ROA2_HUMAN (63-246): 1.97e-38: 141: 38.22
+	Hs
		453344 CUL3_HUMAN (32-759): 0: 814: 38.23		ROA1_HUMAN (58-235): 7.34e-71: 226: 38.38
+	Hs
		1031318 CUL4A_HUMAN (1-759): 0: 963: 100.00		PABP4_HUMAN (144-238): 3.57e-11: 66: 15.63
+	Hs
		516506 CUL4A_HUMAN (1-759): 0: 963: 100.00		PABP1_HUMAN (144-238): 2.78e-10: 63.3: 15.63
+	Hs
		852050 CUL3_HUMAN (32-759): 0: 814: 38.23		ROA3_HUMAN (36-237): 3.44e-53: 180: 36.36
+	Hs
		1031319 CUL4B_HUMAN (10-759): 0: 927: 82.31		PABP4_HUMAN (144-238): 3.57e-11: 66: 15.63
+	Hs
		516507 CUL4B_HUMAN (10-759): 0: 927: 82.31		PABP1_HUMAN (144-238): 2.78e-10: 63.3: 15.63
+	Hs
		162039 CUL3_HUMAN (32-759): 0: 814: 38.23		HNRDL_HUMAN (12-332): 3.27e-51: 176: 49.85
+	Hs
		201667 CUL3_HUMAN (32-759): 0: 814: 38.23		MSI1H_HUMAN (53-287): 4.72e-49: 169: 35.15
+	Hs
		609851 CUL3_HUMAN (32-759): 0: 814: 38.23		ROA2_HUMAN (63-246): 1.97e-38: 141: 38.22
+	Hs
		1020253 CUL3_HUMAN (32-759): 0: 814: 38.23		ELAV2_HUMAN (127-235): 2.25e-16: 80.6: 11.82
+	Hs
		516505 CUL3_HUMAN (32-759): 0: 814: 38.23		PABP1_HUMAN (144-238): 2.78e-10: 63.3: 15.63