Protein: ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein)

Gene: ABCB7
Organism: Homo sapiens
Interactions: 130
UniProt ID: O75027

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0015232 - heme transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

269074

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

3

High-throughput

0.694

High

268960

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

15

Small-scale

0.692

High

268977

CFTR
Cystic fibrosis transmembrane conductance regulator

1

11

High-throughput

0.691

High

268995

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.656

High

268981

HEMH
Ferrochelatase, mitochondrial

2

2

Small-scale

0.655

High

269067

OCAD1
OCIA domain-containing protein 1

3

0

High-throughput

0.622

High

269019

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.618

High

240253

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

268962

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

269017

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

269014

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.578

High

269027

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

269012

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

269031

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

269064

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

268972

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

62078

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

8

High-throughput

0.489

High

260813

RAMP3
Receptor activity-modifying protein 3

1

3

High-throughput

0.489

High

268980

TSN8
Tetraspanin-8

1

6

High-throughput

0.489

High

269008

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

7

High-throughput

0.489

High

269021

VSTM1
V-set and transmembrane domain-containing protein 1

1

1

High-throughput

0.489

High

269028

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.489

High

269032

AQP3
Aquaporin-3

1

16

High-throughput

0.489

High

269042

OPALI
Opalin

1

2

High-throughput

0.489

High

269048

PCGF1
Polycomb group RING finger protein 1

1

3

Small-scale

0.489

High

269053

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

269072

CLC2D
C-type lectin domain family 2 member D

1

6

High-throughput

0.489

High

269076

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.489

High

269078

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

268963

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

268964

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

268965

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

268971

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

268974

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

268976

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

268983

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

268986

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

268992

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

268994

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

268999

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

269007

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

269009

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

6

High-throughput

0.479

High

269018

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

269030

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

269034

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

269037

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

269039

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

269040

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

269052

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

269055

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

269057

MTG2
Mitochondrial ribosome-associated GTPase 2

1

3

High-throughput

0.479

High

269061

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.479

High

269066

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

269069

MTCH1
Mitochondrial carrier homolog 1

1

3

High-throughput

0.479

High

269071

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

269077

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

269079

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.479

High

137576

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

268961

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

268966

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

268967

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

268969

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

268985

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

268987

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.458

High

268988

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

268990

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

268991

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

268997

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

269001

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

269005

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

269006

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

269011

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

269015

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

269023

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

269025

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

269033

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

269036

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

269044

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

269046

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

269047

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

269049

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

269050

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

269054

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.458

High

269060

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

269070

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

269075

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

268975

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.457

High

255939

S19A2
Thiamine transporter 1

1

4

High-throughput

0.445

High

268968

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

269013

S39AE
Metal cation symporter ZIP14

1

9

High-throughput

0.445

High

269043

MYCT
Proton myo-inositol cotransporter

1

2

High-throughput

0.445

High

269065

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.445

High

125100

LEG9
Galectin-9

1

14

High-throughput

0.437

High

269068

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.437

High

269073

XPO7
Exportin-7

1

3

High-throughput

0.437

High

217598

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

268978

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.437

High

268979

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

268982

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

268984

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

268989

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

268998

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.437

High

269002

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.437

High

269003

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

269004

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.437

High

269016

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.437

High

269020

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

269022

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

269024

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

269026

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.437

High

269029

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.437

High

269045

CAB45
45 kDa calcium-binding protein

1

1

High-throughput

0.437

High

269056

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

269058

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

269062

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.437

High

856

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

268970

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.407

High

268973

SYPH
Synaptophysin

1

1

High-throughput

0.407

High

268993

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

5

High-throughput

0.407

High

268996

SC5A3
Sodium/myo-inositol cotransporter

1

2

High-throughput

0.407

High

269051

S39A8
Metal cation symporter ZIP8

1

9

High-throughput

0.407

High

221902

FOXS1
Forkhead box protein S1

1

0

High-throughput

0.279

Low

269063

SYF1
Pre-mRNA-splicing factor SYF1

1

0

High-throughput

0.269

Low

269000

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.249

Low

269010

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

269035

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

269038

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

269041

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

269059

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025