HitPredict

Interactor 1: PTC1 (Q13635)
Protein patched homolog 1 (PTC) (PTC1)
Gene: PTCH1

Interactor 2: ITA7 (Q13683)
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]
Gene: ITGA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1447 Hs			1 1181
+	Hs
		613248 PTC1_HUMAN (1-1447): 0: 1579: 100.00		ITA6_HUMAN (11-1159): 0: 1203: 47.84
+	Hs
		864296 PTC1_HUMAN (1-1447): 0: 1579: 100.00		ITA8_HUMAN (1-1140): 0: 868: 26.77
+	Hs
		419203 PTC1_HUMAN (1-1447): 0: 1579: 100.00		ITAV_HUMAN (31-1111): 0: 859: 26.66
+	Hs
		530650 PTC1_HUMAN (1-1447): 0: 1579: 100.00		ITA4_HUMAN (1-1146): 0: 821: 22.84
+	Dm
		218252 PTC_DROME (48-1283): 0: 993: 38.23		ITA3_DROME (21-1131): 0: 705: 20.84