Interactor 1: KU80 (Q04437)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku80) (High affinity DNA-binding factor subunit 2) (Yeast Ku80)
Gene: YKU80
Interactor 2: DNLI4 (Q08387)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase II) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: DNL4
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16314503 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BRCT~Ku, BRCT~Ku_N, DNA_ligase_A_N~Ku_N |
| Common GO terms | GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0006303 - double-strand break repair via nonhomologous end joining |
| Homologous interactions | 6 |
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Last updated: 11Aug2025