HitPredict

Interactor 1: SRBS1 (G5EC32)
Sorbin and SH3 domain-containing protein 1 homolog
Gene: sorb-1

Interactor 2: VINC (P19826)
Vinculin (P107B)
Gene: deb-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	0.60	0.494

Property	Details
Experiments	19447967
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0005925 - focal adhesion GO:0097433 - dense body
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1005 Ce			1 1090
+	Hs
		235472 VINEX_HUMAN (357-1004): 2.66e-41: 164: 17.74		VINC_HUMAN (1-1089): 0: 797: 30.45
+	Hs
		298947 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		VINC_HUMAN (1-1089): 0: 797: 30.45
+	Hs
		575737 SPTN1_HUMAN (456-964): 1.24e-34: 146: 13.37		VINC_HUMAN (1-1089): 0: 797: 30.45
+	Mm
		1113246 SRBS2_MOUSE (392-1004): 3.92e-42: 169: 17.58		VINC_MOUSE (1-1089): 0: 767: 30.55
+	Hs
		575836 SRBS1_HUMAN (878-1003): 1.56e-20: 100: 32.54		VINC_HUMAN (1-1089): 0: 797: 30.45
+	Hs
		575763 DNMBP_HUMAN (521-742): 5.34e-11: 69.3: 15.19		VINC_HUMAN (1-1089): 0: 797: 30.45
+	Dm
		220701 Q86P80_DROME (281-1004): 3.61e-49: 187: 18.06		VINC_DROME (1-690): 3.21e-37: 153: 14.92
+	Dm
		52981 A1Z866_DROME (264-1004): 1.61e-48: 185: 17.59		VINC_DROME (1-690): 3.21e-37: 153: 14.92
+	Dm
		2230 A0A0B4K6W0_DROME (612-1004): 1.8e-45: 181: 25.44		VINC_DROME (1-690): 3.21e-37: 153: 14.92
+	Hs
		716736 DLG5_HUMAN (269-1002): 5.73e-41: 166: 12.50		CTNA1_HUMAN (122-685): 1.34e-38: 158: 14.85
+	Hs
		298955 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		CTNA1_HUMAN (122-685): 1.34e-38: 158: 14.85
+	Hs
		716762 SRBS1_HUMAN (878-1003): 1.56e-20: 100: 32.54		CTNA1_HUMAN (122-685): 1.34e-38: 158: 14.85