HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: PCDA2 (Q9Y5H9)
Protocadherin alpha-2 (PCDH-alpha-2)
Gene: PCDHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2221 Hs			1 948
+	Hs
		1047324 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA4_HUMAN (1-948): 0: 1116: 83.02
+	Hs
		1047361 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA1_HUMAN (1-948): 0: 1107: 83.26
+	Hs
		1047323 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA6_HUMAN (1-948): 0: 1104: 80.63
+	Hs
		1047325 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDAC_HUMAN (1-948): 0: 1079: 80.49
+	Hs
		1047360 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDAA_HUMAN (22-948): 0: 1079: 81.16
+	Hs
		1047358 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGA_HUMAN (1-896): 0: 986: 38.04
+	Hs
		1047356 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDG6_HUMAN (1-896): 0: 979: 38.76
+	Hs
		1047357 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDG3_HUMAN (25-896): 0: 964: 37.89
+	Hs
		1047354 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGH_HUMAN (24-896): 0: 961: 38.17
+	Hs
		1047351 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGL_HUMAN (7-896): 0: 955: 36.85
+	Hs
		1047258 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDC1_HUMAN (18-948): 0: 947: 44.91
+	Hs
		1047353 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGI_HUMAN (2-896): 0: 944: 35.52
+	Hs
		1047352 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGJ_HUMAN (2-896): 0: 935: 37.75
+	Hs
		1047355 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGF_HUMAN (2-896): 0: 935: 36.36
+	Hs
		1047347 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDB5_HUMAN (1-801): 0: 923: 38.00
+	Hs
		1047349 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDBF_HUMAN (1-789): 0: 905: 41.58
+	Hs
		1047362 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDC2_HUMAN (4-447): 1.79e-96: 328: 25.55
+	Hs
		1047322 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGG_HUMAN (3-447): 1.25e-93: 318: 26.54
+	Hs
		1303365 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PCDGI_HUMAN (2-896): 0: 944: 35.52
+	Hs
		1303362 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PCDGG_HUMAN (3-447): 1.25e-93: 318: 26.54