HitPredict

Interactor 1: MRT2 (G5EC44)
Cell cycle checkpoint protein RAD1 homolog mrt-2 (EC 3.1.11.2)
Gene: mrt-2

Interactor 2: PCNA (O02115)
Proliferating cell nuclear antigen (PCNA)
Gene: pcn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.668

Property	Details
Experiments	12679813, 11778048, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 267 Ce			1 263
+	Bt
		1114084 PCNA_BOVIN (1-267): 8.81e-92: 273: 14.96		PCNA_BOVIN (1-260): 6.06e-110: 319: 47.69
+	Cg
		884983 PCNA_CRIGR (1-267): 8.43e-91: 271: 14.96		PCNA_CRIGR (1-260): 7.97e-110: 319: 48.08
+	Hs
		517023 PCNA_HUMAN (1-267): 3.41e-91: 271: 14.96		PCNA_HUMAN (1-260): 1.5e-109: 318: 48.08
+	Dm
		572163 PCNA_DROME (1-267): 1.6e-89: 267: 18.25		PCNA_DROME (1-261): 1.22e-109: 318: 47.89
+	At
		1341245 PCNA1_ARATH (1-267): 1.18e-88: 265: 18.61		PCNA1_ARATH (1-263): 7.43e-109: 316: 51.71
+	At
		1341247 PCNA1_ARATH (1-267): 1.18e-88: 265: 18.61		PCNA2_ARATH (1-262): 8.65e-107: 311: 50.38
+	At
		1378417 PCNA2_ARATH (1-267): 3.71e-87: 261: 18.98		PCNA2_ARATH (1-262): 8.65e-107: 311: 50.38
+	Dm
		572214 PCNA_DROME (1-267): 1.6e-89: 267: 18.25		PCNA2_DROME (1-260): 6.36e-97: 286: 41.15
+	Ce
		137343 PCNA_CAEEL (1-267): 5.54e-78: 238: 15.33		PCNA_CAEEL (1-263): 1.99e-102: 300: 100.00
+	Dm
		1368110 PCNA2_DROME (1-266): 7.91e-81: 245: 17.54		PCNA2_DROME (1-260): 6.36e-97: 286: 41.15
+	Sp
		976163 PCNA_SCHPO (1-267): 1.13e-78: 240: 17.52		PCNA_SCHPO (1-261): 4.53e-99: 291: 49.04
+	Ca
		1124290 Q5AMN0_CANAL (1-267): 1.94e-70: 219: 17.95		Q5AMN0_CANAL (1-260): 1.39e-91: 272: 43.46
+	Sc
		550511 PCNA_YEAST (1-267): 1.59e-68: 214: 16.61		PCNA_YEAST (1-260): 3.22e-92: 274: 40.39
+	Hs
		238246 RAD1_HUMAN (16-265): 6.09e-80: 244: 28.79		RAD1_HUMAN (2-261): 7.37e-68: 213: 13.97
+	Dm
		1372520 Q9VQD4_DROME (6-267): 2.55e-72: 224: 21.56		Q9VQD4_DROME (2-259): 1.39e-62: 199: 15.13
+	Tk
		1126783 PCNA1_THEKO (12-266): 8.14e-53: 173: 20.16		PCNA1_THEKO (2-258): 7.61e-76: 232: 22.57
+	Tk
		1126788 PCNA2_THEKO (12-266): 9.8e-34: 124: 15.83		PCNA2_THEKO (2-258): 3.56e-75: 230: 20.93