Interactor 1: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1
Interactor 2: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.773 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25628777, 26536456, 22302998, 27212020, 22331464, 28638054, 28533375, 28939422, 24844779, 30473361, 30122040, 29423025, 30778200, 30765703, 30383469, 30793592, 31695040, 32206121, 31169361, 29792731 and 89 others
more... |
| Identification Methods | affinity chromatography technology, pull down, fluorescent resonance energy transfer, protein complementation assay, unspecified method, two hybrid, enzymatic study, proximity labelling technology, x-ray crystallography, anti bait coimmunoprecipitation and 7 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0034599 - cellular response to oxidative stress and 1 others more... |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
