Interactor 1: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 15082779, 16628223, 25742295, 17467235, 12473661, 10428811, 28514442, 32203420, 33961781, 35271311, unassigned2213, 21295525, 16787945
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArfGap~PH, GIT_SHD~RhoGEF67_u2
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0043005 - neuron projection
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 803
Hs

1 761
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024