HitPredict

Interactor 1: FHL2 (Q14192)
Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
Gene: FHL2

Interactor 2: TB182 (Q9C0C2)
182 kDa tankyrase-1-binding protein
Gene: TNKS1BP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.618

Property	Details
Experiments	33961781, 33787085
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 279 Hs			1 1729
+	Hs
		1050765 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		K1671_HUMAN (1548-1728): 1.54e-31: 137: 32.29
+	Hs
		1050839 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		MAGL2_HUMAN (1-758): 2.29e-10: 68.2: 11.08
+	Hs
		1050738 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		CBP_HUMAN (401-826): 3.17e-10: 67.8: 11.48
+	Hs
		257611 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		ANR17_HUMAN (1-411): 1.22e-09: 65.8: 12.56
+	Hs
		1056987 ZN768_HUMAN (37-277): 1.46e-63: 210: 16.34		MDC1_HUMAN (52-890): 1.24e-12: 75.5: 8.70
+	Hs
		1044696 FHL3_HUMAN (66-279): 2.11e-40: 143: 27.32		K1671_HUMAN (1548-1728): 1.54e-31: 137: 32.29
+	Hs
		161768 ZN263_HUMAN (35-278): 1.32e-54: 188: 15.64		ANR17_HUMAN (1-411): 1.22e-09: 65.8: 12.56
+	Dm
		973530 Q2PDT4_DROME (2-159): 3.14e-46: 165: 25.32		CPN_DROME (69-668): 1.07e-15: 85.3: 15.65
+	Dm
		973532 Q8INW7_DROME (2-159): 2.24e-45: 162: 25.32		CPN_DROME (69-668): 1.07e-15: 85.3: 15.65
+	Hs
		1044609 FHL3_HUMAN (66-279): 2.11e-40: 143: 27.32		OBSCN_HUMAN (53-664): 1.02e-14: 82.6: 16.67
+	Hs
		823485 PAXI_HUMAN (187-279): 1.89e-18: 86.9: 23.53		K1671_HUMAN (1548-1728): 1.54e-31: 137: 32.29
+	Hs
		1056958 ZN251_HUMAN (3-176): 9.18e-33: 128: 12.84		MDC1_HUMAN (52-890): 1.24e-12: 75.5: 8.70
+	Ce
		107557 G5EFG1_CAEEL (3-150): 1.53e-19: 90.1: 30.67		UNC89_CAEEL (471-829): 5.54e-14: 80.4: 11.62
+	Ce
		136803 Q3S1I9_CAEEL (3-97): 4.03e-14: 72.6: 42.27		UNC89_CAEEL (471-829): 5.54e-14: 80.4: 11.62
+	Hs
		1044538 FHL1_HUMAN (183-279): 8.68e-11: 63.4: 30.28		MDC1_HUMAN (52-890): 1.24e-12: 75.5: 8.70
+	Hs
		1044561 FHL1_HUMAN (183-279): 8.68e-11: 63.4: 30.28		CBP_HUMAN (401-826): 3.17e-10: 67.8: 11.48