HitPredict

Interactor 1: FHL2 (Q14192)
Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
Gene: FHL2

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 279 Hs			1 1116
+	Hs
		1044706 FHL3_HUMAN (66-279): 2.11e-40: 143: 27.32		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		150593 ABLM1_HUMAN (91-279): 2.1e-38: 145: 21.61		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		73010 ZN879_HUMAN (51-277): 6.46e-57: 193: 13.62		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		1083632 ZNF74_HUMAN (3-184): 2.12e-49: 174: 14.84		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		1050786 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1331283 ZN768_HUMAN (37-277): 1.46e-63: 210: 16.34		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1168455 ZN852_HUMAN (3-125): 3.9e-36: 136: 17.07		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		1231327 ZN251_HUMAN (3-176): 9.18e-33: 128: 12.84		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		200183 TGFI1_HUMAN (3-218): 4.81e-69: 222: 26.39		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93
+	Mm
		1143674 TGFI1_MOUSE (3-218): 1.98e-68: 220: 26.39		ITCH_MOUSE (6-234): 3.37e-28: 124: 16.16
+	Hs
		1231285 ZN606_HUMAN (71-278): 7.19e-27: 111: 11.19		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		563832 ZSC20_HUMAN (183-278): 4.95e-25: 106: 14.42		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		997543 ZN543_HUMAN (3-109): 1.96e-21: 95.7: 12.15		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Ce
		107557 G5EFG1_CAEEL (3-150): 1.53e-19: 90.1: 30.67		UNC89_CAEEL (727-1109): 1.99e-56: 217: 12.25
+	Hs
		1050732 FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		1293396 PDLI5_HUMAN (157-274): 2.08e-30: 121: 24.58		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		816279 LIMS1_HUMAN (3-157): 4.12e-25: 103: 21.80		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1151801 ABLM2_HUMAN (3-212): 5.24e-45: 162: 20.27		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		150606 ABLM1_HUMAN (91-279): 2.1e-38: 145: 21.61		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		816266 LIMS1_HUMAN (3-157): 4.12e-25: 103: 21.80		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15