HitPredict

Interactor 1: EI2BA (Q14232)
Translation initiation factor eIF2B subunit alpha (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: EIF2B1

Interactor 2: 5MP1 (Q9Y6E2)
eIF5-mimic protein 1 (Basic leucine zipper and W2 domain-containing protein 2)
Gene: BZW2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	21745818, 27173435
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 419
+	Hs
		1355663 EI2BD_HUMAN (18-296): 2.47e-93: 287: 24.57		5MP1_HUMAN (1-408): 3.32e-162: 464: 100.00
+	Hs
		834467 EI2BB_HUMAN (2-304): 4.33e-95: 286: 24.92		5MP1_HUMAN (1-408): 3.32e-162: 464: 100.00
+	Hs
		979901 EI2BA_HUMAN (1-305): 2.19e-122: 354: 100.00		IF4G1_HUMAN (19-415): 4.39e-107: 348: 18.80
+	Hs
		1025629 EI2BA_HUMAN (1-305): 2.19e-122: 354: 100.00		EI2BE_HUMAN (240-406): 8.8e-44: 164: 15.61
+	Hs
		1025703 EI2BD_HUMAN (18-296): 2.47e-93: 287: 24.57		EI2BE_HUMAN (240-406): 8.8e-44: 164: 15.61
+	Hs
		834408 EI2BB_HUMAN (2-304): 4.33e-95: 286: 24.92		EI2BE_HUMAN (240-406): 8.8e-44: 164: 15.61
+	Sc
		539961 EI2BA_YEAST (1-304): 6.42e-97: 289: 41.64		EI2BE_YEAST (223-409): 7.32e-42: 158: 14.14
+	Sc
		691728 EI2BB_YEAST (90-298): 1.25e-54: 183: 26.17		EI2BE_YEAST (223-409): 7.32e-42: 158: 14.14
+	Sc
		521177 EI2BD_YEAST (38-272): 1.9e-51: 181: 27.20		EI2BE_YEAST (223-409): 7.32e-42: 158: 14.14