Protein: KDM4D
Lysine-specific demethylase 4D (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3D) (Jumonji domain-containing protein 2D) ([histone H3]-trimethyl-L-lysine(9) demethylase 4D)

Gene: KDM4D
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q6B0I6

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000785 - chromatin
GO:0001932 - regulation of protein phosphorylation
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231215

KDM4D
Lysine-specific demethylase 4D

1

13

Small-scale

0.618

High

414019

P53
Cellular tumor antigen p53

1

3

Small-scale

0.552

High

1209244

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.536

High

65770

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

1

High-throughput

0.536

High

485657

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.536

High

623388

RO52
E3 ubiquitin-protein ligase TRIM21

1

5

High-throughput

0.536

High

687251

HMGB2
High mobility group protein B2

1

4

High-throughput

0.536

High

761714

HSP74
Heat shock 70 kDa protein 4

1

4

High-throughput

0.536

High

913950

RBM5
RNA-binding protein 5

1

1

High-throughput

0.536

High

974581

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.536

High

1088681

SF3A3
Splicing factor 3A subunit 3

1

1

High-throughput

0.536

High

1115252

CUL4B
Cullin-4B

1

4

High-throughput

0.536

High

1119955

CIRBP
Cold-inducible RNA-binding protein

1

2

High-throughput

0.536

High

1148597

SF3A2
Splicing factor 3A subunit 2

1

2

High-throughput

0.536

High

1149089

SF3A1
Splicing factor 3A subunit 1

1

3

High-throughput

0.536

High

1231221

SPF45
Splicing factor 45

1

1

High-throughput

0.536

High

1231226

SF3B6
Splicing factor 3B subunit 6

1

1

High-throughput

0.536

High

1162985

H2B2E
Histone H2B type 2-E

1

9

High-throughput

0.515

High

228285

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.513

High

298008

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

890201

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.513

High

940401

MAZ
Myc-associated zinc finger protein

1

0

High-throughput

0.513

High

1231216

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.513

High

1231220

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1231222

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.513

High

1231223

COPRS
Coordinator of PRMT5 and differentiation stimulator

1

0

High-throughput

0.513

High

1231225

AGO2
Protein argonaute-2

1

0

High-throughput

0.513

High

786668

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

Small-scale

0.508

High

170809

CLGN
Calmegin

1

1

High-throughput

0.489

High

877345

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.489

High

977022

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

2

High-throughput

0.489

High

1051772

EF1A2
Elongation factor 1-alpha 2

1

2

High-throughput

0.489

High

1106272

ROCK1
Rho-associated protein kinase 1

1

3

High-throughput

0.489

High

1231227

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

2

High-throughput

0.489

High

520129

ANDR
Androgen receptor

1

17

Small-scale

0.479

High

1137768

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1220561

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

1231224

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.437

High

1231219

TP4AP
Short transient receptor potential channel 4-associated protein

2

0

High-throughput

0.328

High

1231218

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

428170

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.279

Low

1231217

GPT11
G patch domain-containing protein 11

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025