HitPredict

Interactor 1: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Interactor 2: IPO11 (Q9UI26)
Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)
Gene: IPO11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 29395067
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 975
+	Hs
		892928 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		IPO11_HUMAN (1-975): 0: 643: 100.00
+	Hs
		571625 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		IPO11_HUMAN (1-975): 0: 643: 100.00
+	Dm
		972158 IF4A_DROME (14-407): 0: 510: 73.86		Q9VRV9_DROME (4-881): 5.4e-125: 402: 11.85
+	Sc
		485812 IF4A_YEAST (24-407): 7e-167: 474: 65.89		KA120_YEAST (1-972): 7.8e-117: 385: 24.38
+	Sc
		485823 IF4A_YEAST (24-407): 7e-167: 474: 65.89		SXM1_YEAST (7-973): 1.12e-96: 328: 15.91
+	Sc
		485761 IF4A_YEAST (24-407): 7e-167: 474: 65.89		NMD5_YEAST (8-849): 1.88e-89: 310: 15.31
+	Hs
		163081 DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Hs
		162389 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Hs
		133768 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Xl
		1155771 Q9I8S3_XENLA (22-407): 3.38e-132: 394: 30.46		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43
+	Xl
		1146043 Q66JB0_XENLA (9-407): 1.13e-131: 393: 29.48		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43
+	Xl
		1155738 Q801P9_XENLA (22-407): 2.62e-130: 389: 29.95		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43