HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: BACD1 (Q8WZ19)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein)
Gene: KCTD13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 329
+	Hs
		1045918 FLNC_HUMAN (1-2725): 0: 2507: 100.00		BACD2_HUMAN (23-329): 7.29e-132: 379: 64.50
+	Hs
		1052954 FLNC_HUMAN (1-2725): 0: 2507: 100.00		KCND2_HUMAN (1-237): 1.91e-65: 218: 18.93
+	Hs
		598252 FLNA_HUMAN (167-2725): 0: 1226: 35.27		BACD1_HUMAN (21-329): 1.81e-122: 356: 100.00
+	Hs
		598316 FLNA_HUMAN (167-2725): 0: 1226: 35.27		BACD3_HUMAN (11-324): 1.53e-119: 348: 67.41
+	Hs
		598355 FLNA_HUMAN (167-2725): 0: 1226: 35.27		KCND2_HUMAN (1-237): 1.91e-65: 218: 18.93
+	Hs
		598229 FLNA_HUMAN (167-2725): 0: 1226: 35.27		KCD17_HUMAN (41-192): 1.02e-40: 146: 28.93
+	Hs
		598194 FLNA_HUMAN (167-2725): 0: 1226: 35.27		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33
+	Hs
		261290 FLNB_HUMAN (146-2725): 0: 1198: 35.18		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33
+	Dm
		1364784 FLNA_DROME (758-2724): 0: 1012: 33.19		Q9W579_DROME (29-169): 6.32e-41: 143: 26.71
+	Hs
		521580 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		KCTD6_HUMAN (40-215): 1.51e-41: 146: 28.25
+	Hs
		70404 B2R8Y4_HUMAN (23-388): 3.96e-120: 406: 27.63		KCTD6_HUMAN (40-215): 1.51e-41: 146: 28.25
+	Hs
		993276 ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63		KCTD6_HUMAN (40-215): 1.51e-41: 146: 28.25
+	Hs
		211604 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33
+	Ce
		1095233 Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93		Q9TZA6_CAEEL (36-226): 2.3e-52: 173: 32.00
+	Ce
		954549 Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93		P91563_CAEEL (40-211): 6e-47: 160: 31.61
+	Hs
		963357 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33