Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: UVRAG (Q9P2Y5)
UV radiation resistance-associated gene protein (p63)
Gene: UVRAG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 18641390, 18843052, 19050071, 23878393, 26496610, 30258449, 24956373, 22314358, 27621469, 24879154, 32296183, 19372752, 19270693, 31373534, 33977871, 23954414, 35271311, 34386498, 20562859, 19270696 and 14 others

more...

Identification Methods pull down, affinity chromatography technology, two hybrid, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, isothermal titration calorimetry, two hybrid array, two hybrid prey pooling approach and 1 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005783 - endoplasmic reticulum
GO:0006914 - autophagy
GO:0010506 - regulation of autophagy
and 6 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 450
Hs

1 699
+ Mm
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024