Interactor 1: PSME1 (Q06323)
Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha)
Gene: PSME1
Interactor 2: PSME2 (Q9UL46)
Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta)
Gene: PSME2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311, 28524877, 38334954, 39358380, 31839598, 39422127, 9346951, 16189514, 32296183, 8663520, 33961781, 34349018, 37071682, 19017543, 9325261, unassigned1304, unassigned3799 |
| Identification Methods | affinity chromatography technology, cross-linking study, pull down, two hybrid, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PA28_C~PA28_C, PA28_C~PA28_N, PA28_N~PA28_N |
| Common GO terms | GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008537 - proteasome activator complex and 4 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025
