Interactor 1: PSME3 (P61289)
Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)
Gene: PSME3

Interactor 2: PSME3 (P61289)
Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)
Gene: PSME3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 25416956, 16189514, 27107012, 28292943, 29934401, 30602418, 16169070, 32296183, 31839598, 9325261, 23612972, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, cross-linking study, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PA28_C~PA28_C, PA28_C~PA28_N, PA28_N~PA28_N
Common GO terms GO:0000502 - proteasome complex
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 11 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 254
Hs

1 254
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025