HitPredict

Interactor 1: CASL (Q14511)
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]
Gene: NEDD9

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 834 Hs			1 184
+	Hs
		882205 BCAR1_HUMAN (1-832): 3e-84: 289: 33.44		RAB8A_HUMAN (7-179): 4.93e-85: 251: 29.05
+	Hs
		882207 BCAR1_HUMAN (1-832): 3e-84: 289: 33.44		RAP1B_HUMAN (5-184): 2.05e-37: 129: 38.04
+	Hs
		1186079 MICA3_HUMAN (56-623): 2.84e-41: 166: 10.23		RAB8B_HUMAN (7-180): 2.12e-85: 251: 29.55
+	Hs
		894754 MICA3_HUMAN (56-623): 2.84e-41: 166: 10.23		RAB8A_HUMAN (7-179): 4.93e-85: 251: 29.05
+	Hs
		882657 BCAR1_HUMAN (1-832): 3e-84: 289: 33.44		RAP2C_HUMAN (19-164): 5.1e-31: 112: 39.04
+	Hs
		914166 MICA3_HUMAN (56-623): 2.84e-41: 166: 10.23		RB11A_HUMAN (4-180): 7.77e-76: 228: 29.78
+	Hs
		914020 DYST_HUMAN (403-825): 1.13e-34: 146: 11.63		RB11A_HUMAN (4-180): 7.77e-76: 228: 29.78
+	Hs
		914272 SH3K1_HUMAN (8-74): 1.37e-11: 70.1: 31.34		RB11A_HUMAN (4-180): 7.77e-76: 228: 29.78