Interactor 1: CSP3 (G5ECW5)
Non-catalytic caspase homolog csp-3
Gene: csp-3

Interactor 2: CED3 (P42573)
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]
Gene: ced-3

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.761

The method score is based on:

Property Details
Experiments 18776901
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, protease assay, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C14~Peptidase_C14
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0043525 - positive regulation of neuron apoptotic process
GO:1901046 - positive regulation of egg-laying behavior
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 139
Ce

1 503
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024