HitPredict - High confidence protein-protein interactions

Interactor 1: DMC1 (Q14565)
Meiotic recombination protein DMC1/LIM15 homolog
Gene: DMC1

Interactor 2: DMC1 (Q14565)
Meiotic recombination protein DMC1/LIM15 homolog
Gene: DMC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.920

Property	Details
Experiments	25416956, 15917243, 33446654, 25502805, 31515488
Identification Methods	two hybrid, x-ray crystallography, pull down, two hybrid array
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	HHH_5~HHH_5, HHH_5~Rad51, Rad51~Rad51
Common GO terms	GO:0000150 - DNA strand exchange activity GO:0000730 - DNA recombinase assembly GO:0000781 - chromosome, telomeric region GO:0000794 - condensed nuclear chromosome GO:0000800 - lateral element and 23 others more... GO:0001541 - ovarian follicle development GO:0001556 - oocyte maturation GO:0003677 - DNA binding GO:0003690 - double-stranded DNA binding GO:0003697 - single-stranded DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005694 - chromosome GO:0006312 - mitotic recombination GO:0007129 - homologous chromosome pairing at meiosis GO:0007131 - reciprocal meiotic recombination GO:0007141 - male meiosis I GO:0007283 - spermatogenesis GO:0007286 - spermatid development GO:0007292 - female gamete generation GO:0008094 - ATP-dependent activity, acting on DNA GO:0016887 - ATP hydrolysis activity GO:0035861 - site of double-strand break GO:0042148 - DNA strand invasion GO:0051321 - meiotic cell cycle GO:0070192 - chromosome organization involved in meiotic cell cycle GO:0140664 - ATP-dependent DNA damage sensor activity GO:1990918 - double-strand break repair involved in meiotic recombination
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1	340
Hs

1	340

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024