HitPredict

Interactor 1: RRP1B (Q14684)
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)
Gene: RRP1B

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37689310, 20926688
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0005730 - nucleolus and 1 others more... GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 446
+	Hs
		997725 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		1057682 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		NLE1_HUMAN (338-445): 4.67e-18: 88.1: 13.89
+	Sc
		715480 RRP1_YEAST (12-258): 2.73e-71: 236: 27.93		RRB1_YEAST (7-446): 1.01e-73: 241: 32.89
+	Hs
		903374 KMT2C_HUMAN (211-746): 8e-10: 64.9: 9.09		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Ce
		557846 RPB1_CAEEL (387-747): 1.18e-18: 93.4: 11.89		LIN53_CAEEL (41-247): 1.86e-21: 97.7: 10.33
+	Hs
		997967 CABIN_HUMAN (253-751): 3.01e-10: 66: 9.13		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71