HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 4544
+	Hs
		105912 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		NID2_HUMAN (1679-1844): 1.09e-11: 74.1: 24.86
+	Hs
		106379 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SORL_HUMAN (1080-1344): 6.87e-10: 68.3: 13.65
+	Hs
		105068 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		LDLR_HUMAN (4098-4307): 8.05e-10: 67.6: 13.72
+	Hs
		105248 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		NID1_HUMAN (3259-3502): 3.72e-09: 65.6: 13.18