HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 2214
+	Hs
		106526 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SORT_HUMAN (60-756): 1.92e-179: 571: 28.88
+	Hs
		105865 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PTPRS_HUMAN (1571-2022): 4.91e-53: 209: 19.15
+	Hs
		105068 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		LDLR_HUMAN (1077-1278): 2.78e-29: 129: 34.48
+	Hs
		105365 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		TENA_HUMAN (1653-1934): 3.75e-12: 74.6: 12.94
+	Hs
		105814 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		LRP1_HUMAN (1155-1311): 3.67e-09: 64.6: 21.82