HitPredict

Interactor 1: KCNB1 (Q14721)
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)
Gene: KCNB1

Interactor 2: KCNV1 (Q6PIU1)
Potassium voltage-gated channel subfamily V member 1 (Neuronal potassium channel alpha subunit HNKA) (Voltage-gated potassium channel subunit Kv8.1)
Gene: KCNV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	8670833
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms	GO:0005886 - plasma membrane GO:0008076 - voltage-gated potassium channel complex GO:0051260 - protein homooligomerization GO:0071805 - potassium ion transmembrane transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 500
+	Hs
		1058645 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB2_HUMAN (16-497): 6.27e-137: 419: 41.25
+	Hs
		1058633 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB1_HUMAN (16-497): 1.47e-136: 416: 41.57
+	Mm
		61654 KCNB1_MOUSE (1-858): 0: 712: 93.71		KCNB2_MOUSE (16-497): 2.52e-137: 420: 41.25
+	Hs
		1058647 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNS3_HUMAN (28-497): 4.11e-115: 350: 39.72
+	Hs
		1058644 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNV2_HUMAN (29-463): 7.92e-112: 343: 38.73
+	Hs
		1273152 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNB2_HUMAN (16-497): 6.27e-137: 419: 41.25
+	Hs
		1058643 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG4_HUMAN (6-472): 5.47e-106: 327: 33.20
+	Hs
		1058649 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG1_HUMAN (19-451): 3.69e-103: 320: 35.03
+	Hs
		1161871 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNV1_HUMAN (1-500): 1.72e-134: 399: 100.00
+	Hs
		1273157 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNF1_HUMAN (20-495): 3.85e-118: 357: 32.58
+	Hs
		1273155 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNS3_HUMAN (28-497): 4.11e-115: 350: 39.72
+	Hs
		1058642 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG3_HUMAN (43-443): 1.2e-77: 251: 35.83
+	Hs
		1255150 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG4_HUMAN (6-472): 5.47e-106: 327: 33.20
+	Hs
		1273162 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG1_HUMAN (19-451): 3.69e-103: 320: 35.03
+	Hs
		1058651 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG2_HUMAN (43-460): 2.15e-69: 231: 36.49
+	Hs
		1251106 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG3_HUMAN (43-443): 1.2e-77: 251: 35.83
+	Hs
		569033 KCNA6_HUMAN (2-429): 3.18e-167: 497: 32.31		KCNA3_HUMAN (20-450): 3.15e-114: 350: 28.20