Interactor 1: RPGF (G5EDB9)
Rap guanine nucleotide exchange factor (RA-GEF) (PDZ-domain-containing exchange factor)
Gene: pxf-1

Interactor 2: LET60 (P22981)
Ras protein let-60 (Abnormal cell lineage protein 34) (Lethal protein 60)
Gene: let-60

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 10608844
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~Ras, RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1470
Ce

1 184
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024