HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: BAZ1B (Q9UIG0)
Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)
Gene: BAZ1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28977666, 32744500
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD, Bromodomain~PHD, PHD~PHD
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0008270 - zinc ion binding and 1 others more... GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 1483
+	Hs
		1018738 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BAZ1B_HUMAN (1-1483): 0: 1032: 100.00
+	Hs
		1059928 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BAZ2A_HUMAN (928-1448): 2.16e-77: 286: 19.06
+	Hs
		1059813 CHD4_HUMAN (1-1912): 0: 1719: 100.00		RSF1_HUMAN (477-1311): 3.83e-39: 161: 12.77
+	Hs
		998717 CHD4_HUMAN (1-1912): 0: 1719: 100.00		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		631426 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Mm
		70929 CHD4_MOUSE (1-1900): 0: 1680: 97.80		EP300_MOUSE (1227-1460): 1.9e-39: 163: 17.23
+	Hs
		1017295 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BPTF_HUMAN (1344-1440): 3.78e-27: 123: 31.96
+	Hs
		244447 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		1059625 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BRD3_HUMAN (1331-1447): 6.43e-21: 101: 22.69
+	Hs
		1059704 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PB1_HUMAN (1361-1483): 7.39e-18: 92.5: 21.95
+	Hs
		1059944 CHD4_HUMAN (1-1912): 0: 1719: 100.00		TRI33_HUMAN (1095-1321): 9.51e-15: 82.2: 16.74
+	Hs
		1059760 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PHIP_HUMAN (1338-1418): 2.9e-09: 64.3: 40.00
+	Hs
		998619 CHD3_HUMAN (23-1905): 0: 1595: 66.89		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		631414 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		1017286 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BPTF_HUMAN (1344-1440): 3.78e-27: 123: 31.96
+	Hs
		1017327 CHD5_HUMAN (86-1909): 0: 1584: 71.18		BPTF_HUMAN (1344-1440): 3.78e-27: 123: 31.96
+	Hs
		1018704 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BAZ1A_HUMAN (1267-1463): 1.71e-22: 107: 17.59
+	Hs
		244356 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		1018557 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PB1_HUMAN (1361-1483): 7.39e-18: 92.5: 21.95
+	Hs
		1255033 CHD5_HUMAN (86-1909): 0: 1584: 71.18		PHIP_HUMAN (1338-1418): 2.9e-09: 64.3: 40.00