Protein: KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1)

Gene: KHDR2, KHDRBS2
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q5VWX1

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

284680

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

8

15

High-throughput

0.969

High

1059867

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

5

15

High-throughput

0.920

High

965722

HNRPK
Heterogeneous nuclear ribonucleoprotein K

5

19

High-throughput

0.920

High

1219104

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

14

High-throughput

0.801

High

794514

RBMX
RNA-binding motif protein, X chromosome

7

19

High-throughput

0.754

High

1023247

RBM3
RNA-binding protein 3

5

20

High-throughput

0.722

High

714624

TYK2
Non-receptor tyrosine-protein kinase TYK2

4

20

High-throughput

0.703

High

1219138

YTDC1
YTH domain-containing protein 1

4

7

High-throughput

0.700

High

1219127

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

3

2

High-throughput

0.692

High

1219156

FBW1B
F-box/WD repeat-containing protein 11

4

7

High-throughput

0.691

High

140308

SDCB1
Syntenin-1

3

4

High-throughput

0.675

High

214849

HNRPR
Heterogeneous nuclear ribonucleoprotein R

3

9

High-throughput

0.669

High

1219158

FBW1A
F-box/WD repeat-containing protein 1A

3

8

High-throughput

0.662

High

1219159

CHTOP
Chromatin target of PRMT1 protein

3

0

High-throughput

0.646

High

1219147

NCOA5
Nuclear receptor coactivator 5

3

3

High-throughput

0.637

High

130500

SPT5H
Transcription elongation factor SPT5

2

2

High-throughput

0.628

High

691772

MK03
Mitogen-activated protein kinase 3

2

1

High-throughput

0.628

High

938016

FOXA3
Hepatocyte nuclear factor 3-gamma

2

2

High-throughput

0.628

High

1112543

CUL1
Cullin-1

2

4

High-throughput

0.628

High

1137348

SUZ12
Polycomb protein SUZ12

2

2

High-throughput

0.628

High

1219109

ACD11
Acyl-CoA dehydrogenase family member 11

2

3

High-throughput

0.628

High

1219120

COP1
E3 ubiquitin-protein ligase COP1

2

4

High-throughput

0.628

High

1219132

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

4

High-throughput

0.628

High

1118412

PTK6
Protein-tyrosine kinase 6

2

20

High-throughput

0.628

High

1119953

CIRBP
Cold-inducible RNA-binding protein

2

18

High-throughput

0.628

High

135238

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

20

High-throughput

0.618

High

1219151

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

19

High-throughput

0.618

High

1009219

PRR3
Proline-rich protein 3

3

2

High-throughput

0.616

High

1219119

CTSR1
Cation channel sperm-associated protein 1

3

4

High-throughput

0.616

High

1219130

DOCK2
Dedicator of cytokinesis protein 2

3

3

High-throughput

0.616

High

1219149

NPDC1
Neural proliferation differentiation and control protein 1

3

1

High-throughput

0.616

High

1033016

EWS
RNA-binding protein EWS

2

10

High-throughput

0.608

High

829228

RFC3
Replication factor C subunit 3

2

1

High-throughput

0.606

High

1040491

HHEX
Hematopoietically-expressed homeobox protein HHEX

2

1

High-throughput

0.606

High

1219107

FX4L3
Forkhead box protein D4-like 3

2

2

High-throughput

0.606

High

1219123

BAHD1
Bromo adjacent homology domain-containing 1 protein

2

1

High-throughput

0.606

High

1219137

ZN837
Zinc finger protein 837

2

1

High-throughput

0.606

High

1219139

RBM14
RNA-binding protein 14

2

11

High-throughput

0.606

High

1219152

ZN581
Zinc finger protein 581

2

1

High-throughput

0.606

High

818743

CAPG
Macrophage-capping protein

2

0

High-throughput

0.602

High

1179174

CTC1
CST complex subunit CTC1

2

0

High-throughput

0.602

High

1219141

CRBN
Protein cereblon

2

0

High-throughput

0.602

High

1096336

ROA0
Heterogeneous nuclear ribonucleoprotein A0

2

17

High-throughput

0.586

High

1219108

ZN497
Zinc finger protein 497

2

0

High-throughput

0.580

High

479214

THIK
3-ketoacyl-CoA thiolase, peroxisomal

2

1

High-throughput

0.574

High

619068

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

2

1

High-throughput

0.574

High

1141455

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

2

1

High-throughput

0.574

High

1208361

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

2

4

High-throughput

0.574

High

1219154

KLH42
Kelch-like protein 42

2

1

High-throughput

0.574

High

1219155

NAGK
N-acetyl-D-glucosamine kinase

2

1

High-throughput

0.574

High

380705

HBAZ
Hemoglobin subunit zeta

2

2

High-throughput

0.573

High

1102569

MTA1
Metastasis-associated protein MTA1

1

1

High-throughput

0.573

High

1219133

SOSB2
SOSS complex subunit B2

1

1

High-throughput

0.573

High

292840

GRAP2
GRB2-related adapter protein 2

1

20

High-throughput

0.560

High

611738

BMP7
Bone morphogenetic protein 7

2

2

High-throughput

0.553

High

1203969

DALD3
DALR anticodon-binding domain-containing protein 3

2

1

High-throughput

0.553

High

1219113

LMTD2
Lamin tail domain-containing protein 2

2

1

High-throughput

0.553

High

1219118

CNNM3
Metal transporter CNNM3

2

1

High-throughput

0.553

High

1219122

LNX1
E3 ubiquitin-protein ligase LNX

2

5

High-throughput

0.553

High

1219125

AEN
Apoptosis-enhancing nuclease

1

0

High-throughput

0.549

High

1023089

RBM10
RNA-binding protein 10

1

8

High-throughput

0.541

High

1115723

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.536

High

170193

AURKA
Aurora kinase A

1

0

High-throughput

0.513

High

1219111

FBX11
F-box only protein 11

1

0

High-throughput

0.513

High

1219128

PSMF1
Proteasome inhibitor PI31 subunit

1

2

High-throughput

0.512

High

1219153

NHSL3
NHS-like protein 3

1

2

High-throughput

0.489

High

211340

RFOX2
RNA binding protein fox-1 homolog 2

1

19

High-throughput

0.481

High

244713

ZC3H1
Zinc finger C3H1 domain-containing protein

1

1

High-throughput

0.481

High

505721

ZN688
Zinc finger protein 688

1

3

High-throughput

0.481

High

1005798

RPP30
Ribonuclease P protein subunit p30

1

1

High-throughput

0.481

High

1148504

SF3B4
Splicing factor 3B subunit 4

1

13

High-throughput

0.481

High

1150735

SF01
Splicing factor 1

1

17

High-throughput

0.481

High

1219126

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

13

High-throughput

0.481

High

1219135

MSI2H
RNA-binding protein Musashi homolog 2

1

18

High-throughput

0.481

High

138163

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.479

High

162598

ANM5
Protein arginine N-methyltransferase 5

1

7

High-throughput

0.479

High

172127

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

20

High-throughput

0.479

High

250653

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

9

High-throughput

0.479

High

331044

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.479

High

462462

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

17

High-throughput

0.479

High

463579

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.479

High

485204

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

18

High-throughput

0.479

High

576430

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

13

High-throughput

0.479

High

608631

DDX5
Probable ATP-dependent RNA helicase DDX5

1

9

High-throughput

0.479

High

650805

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

14

High-throughput

0.479

High

729071

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

9

High-throughput

0.479

High

729306

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

12

High-throughput

0.479

High

775676

DEK
Protein DEK

1

2

High-throughput

0.479

High

904829

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

994593

YBOX1
Y-box-binding protein 1

1

8

High-throughput

0.479

High

1089436

ILF2
Interleukin enhancer-binding factor 2

1

9

High-throughput

0.479

High

1089708

ILF3
Interleukin enhancer-binding factor 3

1

10

High-throughput

0.479

High

1096042

TADBP
TAR DNA-binding protein 43

1

13

High-throughput

0.479

High

1120197

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

18

High-throughput

0.479

High

1126945

RBM39
RNA-binding protein 39

1

16

High-throughput

0.479

High

1148426

SAFB1
Scaffold attachment factor B1

1

14

High-throughput

0.479

High

1168819

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

4

High-throughput

0.479

High

1218880

TAF3
Transcription initiation factor TFIID subunit 3

1

3

High-throughput

0.479

High

1219112

HORN
Hornerin

1

1

High-throughput

0.479

High

1219114

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

1

High-throughput

0.479

High

1219116

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1219117

EHBP1
EH domain-binding protein 1

1

2

High-throughput

0.479

High

1219131

DDX17
Probable ATP-dependent RNA helicase DDX17

1

9

High-throughput

0.479

High

1219142

ANM1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.479

High

1219143

MEP50
Methylosome protein WDR77

1

7

High-throughput

0.479

High

1219148

MOV10
Helicase MOV-10

1

4

High-throughput

0.479

High

108035

G3V1X1
Proline/serine-rich coiled-coil 2, isoform CRA_a

1

1

High-throughput

0.470

High

468485

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.458

High

658228

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

1036748

DSG1
Desmoglein-1

1

0

High-throughput

0.458

High

1219105

ARID2
AT-rich interactive domain-containing protein 2

1

0

High-throughput

0.458

High

515841

RBY1A
RNA-binding motif protein, Y chromosome, family 1 member A1

1

20

High-throughput

0.457

High

1148276

RBY1F
RNA-binding motif protein, Y chromosome, family 1 member F/J

1

18

High-throughput

0.457

High

129744

CBX4
E3 SUMO-protein ligase CBX4

1

2

High-throughput

0.445

High

1219140

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

5

High-throughput

0.445

High

1219144

DIDO1
Death-inducer obliterator 1

1

8

High-throughput

0.445

High

387724

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

2

High-throughput

0.437

High

387845

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.437

High

387975

FIBG
Fibrinogen gamma chain

1

2

High-throughput

0.437

High

1116218

PTC1
Protein patched homolog 1

1

2

Small-scale

0.437

High

1219124

LRC15
Leucine-rich repeat-containing protein 15

1

1

High-throughput

0.437

High

3542

A0A0S2Z5X4
Zinc finger protein 688 isoform 4

1

3

High-throughput

0.417

High

334194

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

3

0

High-throughput

0.345

High

1042701

KIME
Mevalonate kinase

2

0

High-throughput

0.328

High

1219110

YRDC
Threonylcarbamoyl-AMP synthase

2

0

High-throughput

0.328

High

1219134

PTER
N-acetyltaurine hydrolase

2

0

High-throughput

0.328

High

516061

ST1A4
Sulfotransferase 1A4

1

0

High-throughput

0.299

High

1219121

TYMOS
TYMS opposite strand protein

1

0

High-throughput

0.299

High

1219157

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

0

High-throughput

0.299

High

1219115

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.279

Low

1219150

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.265

Low

1219129

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.249

Low

1219145

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.249

Low

1219106

TWF2
Twinfilin-2

1

0

High-throughput

0.232

Low

1219136

MUCL1
Mucin-like protein 1

1

0

High-throughput

0.232

Low

1219146

YIPF3
Protein YIPF3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025