Interactor 1: G5EDI8 (G5EDI8)
Dicer-related helicase (RNA helicase)
Gene: drh-1

Interactor 2: DCR1 (P34529)
Endoribonuclease dcr-1 (EC 3.1.26.-) [Cleaved into: Death-promoting deoxyribonuclease (tDCR-1) (EC 3.1.21.-)]
Gene: dcr-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 16439208, 22179787
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Dicer_dimer, DEAD~Helicase_C, DEAD~Ribonuclease_3, Helicase_C~Helicase_C, Helicase_C~ResIII, Helicase_C~RIG-I_C-RD, RIG-I_C-RD~ResIII
Common GO terms GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1037
Ce

1 1910
+ At
+ At
+ At
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024